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Paula G. Ragone
Researcher at National University of Salta
Publications - 20
Citations - 331
Paula G. Ragone is an academic researcher from National University of Salta. The author has contributed to research in topics: Trypanosoma cruzi & Chagas disease. The author has an hindex of 10, co-authored 20 publications receiving 306 citations.
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Journal ArticleDOI
Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: validation using parasite stocks from the Chaco Region and a set of reference strains.
Juan José Lauthier,Nicolás Tomasini,Christian Barnabé,Maria Mercedes Monje Rumi,Anahí M. Alberti D’Amato,Paula G. Ragone,Matthew Yeo,Michael D. Lewis,Martin S. Llewellyn,Miguel A. Basombrío,Michael A. Miles,Michel Tibayrenc,Patricio Diosque +12 more
TL;DR: It is suggested that MLST will have a strong impact on molecular epidemiological studies of Chagas disease and the phylogenetics of its causative agent and is an excellent candidate to become the gold standard for T. cruzi genetic typing.
Journal ArticleDOI
Trypanosoma cruzi diversity in the Gran Chaco: Mixed infections and differential host distribution of TcV and TcVI
María M. Monje-Rumi,Cecilia Pérez Brandán,Paula G. Ragone,Nicolás Tomasini,Juan José Lauthier,Anahí M. Alberti D’Amato,Rubén O. Cimino,Viviana Orellana,Miguel A. Basombrío,Patricio Diosque +9 more
TL;DR: The occurrence of one human infected whit TcIII (a principally wild DTU) could be suggested the emergence of this, in domestic cycles in the Gran Chaco.
Journal ArticleDOI
Interest and limitations of Spliced Leader Intergenic Region sequences for analyzing Trypanosoma cruzi I phylogenetic diversity in the Argentinean Chaco.
Nicolás Tomasini,Juan José Lauthier,Maria Mercedes Monje Rumi,Paula G. Ragone,Anahí A. Alberti D’Amato,Cecilia Pérez Brandán,Carolina Cura,Alejandro G. Schijman,Christian Barnabé,Michel Tibayrenc,Miguel A. Basombrío,Alejandra Falla,Claudia Herrera,Felipe Guhl,Patricio Diosque +14 more
TL;DR: Since there are multiple copies of the SL-IR, and they are arranged in tandem, it is discussed how molecular processes affecting this kind of sequences could mislead phylogenetic inference.
Journal ArticleDOI
Optimized multilocus sequence typing (MLST) scheme for Trypanosoma cruzi.
Patricio Diosque,Nicolás Tomasini,Juan José Lauthier,Louisa A. Messenger,Maria Mercedes Monje Rumi,Paula G. Ragone,Anahí Maitén Alberti-D'Amato,Cecilia Pérez Brandán,Christian Barnabé,Michel Tibayrenc,Michael D. Lewis,Martin S. Llewellyn,Michael A. Miles,Matthew Yeo +13 more
TL;DR: This work presents an optimized Multilocus Sequence Typing (MLST) scheme, based on the combined analysis of two recently proposed MLST approaches, and proposes that the seven-fragment MLST scheme could be used as a gold standard for T. cruzi typing.
Journal ArticleDOI
Immuno-enzymatic evaluation of the recombinant TSSA-II protein of Trypanosoma cruzi in dogs and human sera: a tool for epidemiological studies.
Rubén O. Cimino,M. Monje Rumi,Paula G. Ragone,Juan José Lauthier,A. M. Alberti d'Amato,I. R. López Quiroga,José Fernando Gil,Silvana P. Cajal,Norma Acosta,Marisa Juarez,Alejandro J. Krolewiecki,Viviana Orellana,Rosa Zacca,Iván Sergio Marcipar,Patricio Diosque,Julio R. Nasser +15 more
TL;DR: ELISA-rTSSA-II showed a high performance when studying sera from naturally infected dogs and it also presented 100% Sp, which could be an important tool to carry out sero-epidemiological surveys on the prevalence of T. cruzi circulating lineages in the region.