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Paula Ghaneh
Researcher at University of Liverpool
Publications - 219
Citations - 15603
Paula Ghaneh is an academic researcher from University of Liverpool. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 56, co-authored 204 publications receiving 13631 citations. Previous affiliations of Paula Ghaneh include Royal Liverpool and Broadgreen University Hospital NHS Trust & Royal Liverpool University Hospital.
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Journal ArticleDOI
Prognosis of Resected Ampullary Adenocarcinoma by Preoperative Serum CA19-9 Levels and Platelet-Lymphocyte Ratio
Richard A. Smith,Paula Ghaneh,Robert Sutton,Michael Raraty,Fiona Campbell,John P. Neoptolemos +5 more
TL;DR: Preoperative CA19-9 and PLR both merit further evaluation as prognostic indices in resected ampullary adenocarcinoma.
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ESPAC-5F: Four-arm, prospective, multicenter, international randomized phase II trial of immediate surgery compared with neoadjuvant gemcitabine plus capecitabine (GEMCAP) or FOLFIRINOX or chemoradiotherapy (CRT) in patients with borderline resectable pancreatic cancer.
Paula Ghaneh,Daniel H. Palmer,Silvia Cicconi,Christopher Halloran,Eftychia E. Psarelli,Charlotte L. Rawcliffe,Rajaram Sripadam,Somnath Mukherjee,Jonathan Wadsley,Ahmed Al-Mukhtar,Long R. Jiao,Harpreet Wasan,Ross Carter,Janet Graham,Farooq Ammad,Jonathan P. Evans,Christine Tjaden,Thilo Hackert,Markus W. Büchler,John P. Neoptolemos +19 more
TL;DR: There was no difference in resection rate between arms, however neoadjuvant therapy had a significant survival benefit compared with immediate surgery, and overall survival and toxicity.
Journal ArticleDOI
A new approach to managing intraductal papillary mucinous pancreatic neoplasms
Paula Ghaneh,John P. Neoptolemos +1 more
TL;DR: The association of IPMNs (particularly the gastric type variant) with the precursor lesions of pancreatic ductal adenocarcinoma known as pancreatic intra-epithelial neoplasms (PanINs) or PanIN-like lesions may provide further information concerning their development.
Journal ArticleDOI
Pancreatic Pseudocyst in Chronic Pancreatitis: Endoscopic and Surgical Treatment
Edoardo Rosso,Nicholas Alexakis,Paula Ghaneh,Martin Lombard,Howard Smart,J. Evans,John P. Neoptolemos +6 more
TL;DR: With better knowledge of the disease and with technical advances the indications, timing and methods to treat pancreatic pseudocysts haveundergone a marked evolutionary change.
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PET-PANC:multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer
Paula Ghaneh,Robert Hanson,Andrew Titman,Gillian Lancaster,Catrin Plumpton,Huw Lloyd-Williams,Seow Tien Yeo,Rhiannon Tudor Edwards,Colin D. Johnson,Mohammed Abu Hilal,Antony Higginson,T. Armstrong,Andrew Smith,Andrew Scarsbrook,C. McKay,Ross Carter,Robert P. Sutcliffe,Simon R. Bramhall,Hemant M. Kocher,David Cunningham,Stephen P. Pereira,B. Davidson,David Chang,Saboor Khan,Ian Zealley,Debashis Sarker,Bilal Al Sarireh,Richard Charnley,Dileep N. Lobo,Marianne Nicolson,Christopher Halloran,Michael Raraty,Robert Sutton,Sobhan Vinjamuri,Jonathan Evans,Fiona Campbell,Jon Deeks,Bal Sanghera,Wai-Lup Wong,John P. Neoptolemos +39 more
TL;DR: PET/CT provided a significant incremental diagnostic benefit in the diagnosis of pancreatic cancer and significantly influenced the staging and management of patients and is likely to be cost-effective at current reimbursement rates for PET/CT to the UK NHS.