P
Paula Ghaneh
Researcher at University of Liverpool
Publications - 219
Citations - 15603
Paula Ghaneh is an academic researcher from University of Liverpool. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 56, co-authored 204 publications receiving 13631 citations. Previous affiliations of Paula Ghaneh include Royal Liverpool and Broadgreen University Hospital NHS Trust & Royal Liverpool University Hospital.
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Journal ArticleDOI
Optimal Duration and Timing of Adjuvant Chemotherapy After Definitive Surgery for Ductal Adenocarcinoma of the Pancreas: Ongoing Lessons From the ESPAC-3 Study
Juan W. Valle,Daniel H. Palmer,Richard J. Jackson,Trevor Cox,John P. Neoptolemos,Paula Ghaneh,Charlotte L. Rawcliffe,Claudio Bassi,Deborah D. Stocken,David Cunningham,Derek A. O'Reilly,David Goldstein,Bridget A. Robinson,Christos S. Karapetis,Andrew Scarfe,François Lacaine,Juhani Sand,Jakob R. Izbicki,Julia Mayerle,Christos Dervenis,Attila Oláh,Giovanni Butturini,Pehr Lind,Mark R. Middleton,Alan Anthoney,K Sumpter,Ross Carter,Markus W. Büchler +27 more
TL;DR: Completion of all six cycles of planned adjuvant chemotherapy rather than early initiation was an independent prognostic factor after resection for pancreatic adenocarcinoma and there seems to be no difference in outcome if chemotherapy is delayed up to 12 weeks, thus allowing adequate time for postoperative recovery.
Journal ArticleDOI
Current standards of surgery for pancreatic cancer.
Nicholas Alexakis,Christopher Halloran,Michael Raraty,Paula Ghaneh,Robert Sutton,John P. Neoptolemos +5 more
TL;DR: Pancreatic cancer carries a dismal prognosis but there has been a vast increase in evidence on its management in the past decade.
Journal ArticleDOI
Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial
William Greenhalf,Paula Ghaneh,John P. Neoptolemos,Daniel H. Palmer,Trevor Cox,Richard F. Lamb,Elizabeth Garner,Fiona Campbell,John R. Mackey,Eithne Costello,Malcolm J. Moore,Juan W. Valle,A. C. McDonald,Ross Carter,Ross Carter,Niall C. Tebbutt,David Goldstein,Jennifer Shannon,Christos Dervenis,Bengt Glimelius,Mark Deakin,Richard Charnley,François Lacaine,Andrew Scarfe,Mark R. Middleton,Alan Anthoney,Christopher Halloran,Julia Mayerle,Attila Oláh,Richard J. Jackson,Charlotte L. Rawcliffe,Aldo Scarpa,Claudio Bassi,Markus W. Büchler +33 more
TL;DR: Subject to prospective validation, gemcitabine should not be used for patients with low tumor hENT1 expression.
Journal ArticleDOI
Early and late complications after pancreatic necrosectomy.
Saxon Connor,Nicholas Alexakis,Michael Raraty,Paula Ghaneh,J. Evans,M. Hughes,C. Garvey,Robert Sutton,John P. Neoptolemos +8 more
TL;DR: Almost all patients undergoing necrosectomy developed significant early or late complications or both, and Multiorgan failure and postoperative hemorrhage were independent predictors of mortality.
Journal Article
Branch-duct intraductal papillary mucinous neoplasms of the pancreas : to operate or not to operate? Commentary
Paula Ghaneh,John P. Neoptolemos,Roberto Salvia,Stefano Crippa,Massimo Falconi,Claudio Bassi,Alessandro Guarise,Aldo Scarpa,Paolo Pederzoli +8 more
TL;DR: In this paper, the authors evaluated the effectiveness of a follow-up protocol for Branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) and concluded that careful non-operative management seems to be safe and effective in asymptomatic patients.