P
Paula M. Alves
Researcher at Universidade Nova de Lisboa
Publications - 404
Citations - 12349
Paula M. Alves is an academic researcher from Universidade Nova de Lisboa. The author has contributed to research in topics: Cell culture & Medicine. The author has an hindex of 53, co-authored 376 publications receiving 10405 citations. Previous affiliations of Paula M. Alves include Instituto Português de Oncologia Francisco Gentil & University of Lisbon.
Papers
More filters
Journal ArticleDOI
Analysis of adsorption of a baculovirus bioreaction bulk on an ion-exchange surface by surface plasmon resonance.
TL;DR: A model that quantitatively explains the SPR-derived adsorption/desorption data was successfully developed for this complex biological system.
Journal ArticleDOI
Phosphoneurofilament heavy chain and vascular endothelial growth factor as cerebrospinal fluid biomarkers for ALS
Margarida Gonçalves,Mamede de Carvalho,Cristina Peixoto,Paula M. Alves,Carmo Barreto,Abel Oliva,Susana Pinto,Ana Laborinho-Pronto,Marta Gromicho,Júlia Costa +9 more
TL;DR: The diagnostic potential of combining pNFH and VEGF as ALS biomarker is explored and the results are inconsistent.
Journal ArticleDOI
23Na multiple quantum filtered NMR characterisation of Na+ binding and dynamics in animal cells: a comparative study and effect of Na+/Li+ competition
Carla P. Fonseca,Luís L. Fonseca,Liliana P. Montezinho,Paula M. Alves,Helena Santos,M. Margarida C. A. Castro,Carlos F. G. C. Geraldes +6 more
TL;DR: Double quantum and triple quantum filtered 23Na nuclear magnetic resonance techniques were used to characterise in detail the isotropic and anisotropic binding and dynamics of intra- and extracellular Na+ in different cellular systems, in the absence and presence of Li+.
Journal ArticleDOI
Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice.
TL;DR: TDZD-8 reduces the inflammatory response associated with TNBS-induced colitis in mice, and modulation of GSK-3β seems to be an interesting pharmacological target in colitis.
Journal ArticleDOI
Production of rotavirus core-like particles in Sf9 cells using recombinase-mediated cassette exchange
Fabiana Fernandes,Mafalda M. Dias,João Vidigal,Marcos F. Q. Sousa,Marco Patrone,Ana P. Teixeira,Paula M. Alves +6 more
TL;DR: Overall, it is shown that this Sf9-Flp cell platform represents a valuable alternative to the BEVS for producing complex recombinant proteins, such as rotavirus core-like particles.