P
Pauline Krijgsheld
Researcher at Utrecht University
Publications - 14
Citations - 909
Pauline Krijgsheld is an academic researcher from Utrecht University. The author has contributed to research in topics: Mycelium & Aspergillus niger. The author has an hindex of 10, co-authored 14 publications receiving 667 citations.
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Journal ArticleDOI
Development in Aspergillus
Pauline Krijgsheld,Robert-Jan Bleichrodt,G.J. van Veluw,Fengfeng Wang,Wally H. Müller,Jan Dijksterhuis,Han A. B. Wösten +6 more
TL;DR: The molecular mechanisms underlying growth and development of Aspergillus are described, including conidiophores and ascocarps are produced that form conidia and ascospores, respectively.
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Fabrication factors influencing mechanical, moisture- and water-related properties of mycelium-based composites
Freek V.W. Appels,Serena Camere,Maurizio Montalti,Elvin Karana,Kaspar M. B. Jansen,Jan Dijksterhuis,Pauline Krijgsheld,Han A. B. Wösten +7 more
TL;DR: In this article, the authors show that mycelium-based composites can be tuned by varying type of substrate (straw, sawdust, cotton), fungal species (Pleurotus ostreatus vs. Trametes multicolor) and processing technique (no pressing or cold or heat pressing).
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Germination of conidia of aspergillus niger is accompanied by major changes in RNA profiles
M.R. van Leeuwen,Pauline Krijgsheld,Robert-Jan Bleichrodt,Hildegard Henna Menke,Hein Stam,J. Stark,Han A. B. Wösten,Jan Dijksterhuis +7 more
TL;DR: The transcriptome of conidia of Aspergillus niger changes dramatically during the first two h and that initiation of protein synthesis and respiration are important during early stages of germination.
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Hydrophobin gene deletion and environmental growth conditions impact mechanical properties of mycelium by affecting the density of the material
Freek V.W. Appels,Jan Dijksterhuis,Catherine E. Lukasiewicz,Kaspar M. B. Jansen,Han A. B. Wösten,Pauline Krijgsheld +5 more
TL;DR: Mechanical properties of wild type mycelium were similar to those of natural materials, while those of Δsc3 were more similar to thermoplastics.
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Heterogeneity in the mycelium: implications for the use of fungi as cell factories.
TL;DR: The findings imply that productivity in a bioreactor may be increased by reducing the heterogeneity within the culture, and molecular mechanisms underlying productivity of fungi in bioreactors should not be studied at the culture level but at the level of micro-colony populations or even at zonal or hyphal level.