P
Paulo F. Santos
Researcher at University of Trás-os-Montes and Alto Douro
Publications - 66
Citations - 1216
Paulo F. Santos is an academic researcher from University of Trás-os-Montes and Alto Douro. The author has contributed to research in topics: Cyanine & Singlet oxygen. The author has an hindex of 17, co-authored 62 publications receiving 1005 citations. Previous affiliations of Paulo F. Santos include University of Beira Interior & Technical University of Lisbon.
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Journal ArticleDOI
Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)
Liliana P. Ferreira,Edite Teixeira-de-Lemos,Filipa Pinto,Belmiro Parada,C. Mega,Helena Vala,Rui Pinto,Patrícia Garrido,José Sereno,Rosa Fernandes,Paulo F. Santos,Isabel Velada,Andreia Cristina de Melo,Sara Nunes,Frederico Teixeira,Flávio Reis +15 more
TL;DR: Chronic sitagliptin treatment corrected the glycaemic dysmetabolism, hypertriglyceridaemia, inflammation, and hypertension, reduced the severity of the histopathological lesions of pancreatic endocrine and exocrine tissues, together with a favourable redox status, which might be a further advantage in the management of diabetes and its proatherogenic comorbidities.
Journal ArticleDOI
Synthesis and spectroscopic characterisation of n-alkyl quaternary ammonium salts typical precursors of cyanines
TL;DR: In this article, the synthesis and spectroscopic characterisation of representative N-alkylsubstituted quaternary ammonium salts derived from benzothiazole, benzoxazoles, benzoselenazole, indole and quinoline are described.
Journal ArticleDOI
Singlet oxygen generation ability of squarylium cyanine dyes
TL;DR: In this article, the quantum yields for singlet oxygen generation of several squarylium cyanine dyes derived from benzothiazole, benzoselenazole and quinoline, displaying absorption within the so-called phototherapeutic window, were determined, envisioning their potential usefulness for photodynamic therapy (PDT).
Journal ArticleDOI
Efficiency of singlet oxygen generation of aminosquarylium cyanines
Paulo F. Santos,Lucinda V. Reis,Paulo Almeida,J. P. C. Serrano,Anabela S. Oliveira,L.F. Vieira Ferreira +5 more
TL;DR: Several symmetrical N-methylamino and N,N-diethylaminosquarylium cyanine dyes bearing benzothiazole, benzoselenazole and quinoline nuclei, displaying strong absorption within the phototherapeutic window, were investigated for the efficiency of singlet oxygen production, aiming their potential sensitising ability for photodynamic therapy as mentioned in this paper.
Journal ArticleDOI
Synthesis and Photochemical Evaluation of Iodinated Squarylium Cyanine Dyes
Paulo F. Santos,Lucinda V. Reis,Isabel Duarte,João P. Serrano,Paulo Almeida,Anabela S. Oliveira,Luis F. Vieira Ferreira +6 more
TL;DR: Several (multiply) iodinated squarylium cyanine dyes of type 1 and 8 were synthesized as potential new photosensitizers, with absorptions in the 700-nm region as discussed by the authors.