Pavel Spirin

TL;DR: This case represents the mildest phenotype of P 450scc deficiency to be described, and the phenotypic presentation was consistent with the partial reduction of P450scc activity of L222P mutant.

TL;DR: The gene expression database of normal human tissues based on uniformly screened original sequencing data was constructed and deposited, finding that overall 463 biosamples showed tissue-specific rather than platform- or database-specific clustering and could be aggregated in a single database termed Oncobox Atlas of Normal Tissue Expression (ANTE).

TL;DR: It is shown that AML cells transduced with short hairpin RNA vector targeting AE mRNAs have a dramatic decrease in growth rate that is caused by induction of apoptosis and deregulation of the cell cycle.

TL;DR: All natural fucoidans can be considered as potential anti-HIV agents regardless of their carbohydrate backbone and degree of sulfating, since their activity is shown at low concentrations.

TL;DR: Evidence is provided that the cooperative effect of the expression of mutated KIT and AML1-ETO oncogenes is crucial for selective toxic action of binase on malignant cells.