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Pedram Kharaziha
Researcher at Karolinska Institutet
Publications - 23
Citations - 1393
Pedram Kharaziha is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 13, co-authored 22 publications receiving 1219 citations. Previous affiliations of Pedram Kharaziha include Karolinska University Hospital & Shahid Beheshti University.
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Journal ArticleDOI
Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial.
Pedram Kharaziha,Per M. Hellström,Babak Noorinayer,Farivar Farzaneh,Katayoun Aghajani,Fereshteh Jafari,Mohammad Telkabadi,Amir Atashi,Maryam Honardoost,Mohammad Reza Zali,Masoud Soleimani +10 more
TL;DR: The data show that MSCs injection can be used for the treatment of end-stage liver disease with satisfactory tolerability and furthermore, this treatment may improve clinical indices of liver function in end-Stage liver disease.
Journal ArticleDOI
Tumor cell-derived exosomes: a message in a bottle.
TL;DR: The molecular composition and functional role of tumor cell-derived exosomes in tumorigenesis, metastasis and response to therapy are slowly decrypted and the latest findings as well as potential therapeutic strategies are discussed in this review.
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Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Pedram Kharaziha,Dimitris Chioureas,Dorothea Rutishauser,George E. Baltatzis,Lena Lennartsson,Pedro Fonseca,Alireza Azimi,Kjell Hultenby,Roman A. Zubarev,Roman A. Zubarev,Anders Ullén,Jeffrey Yachnin,Sten Nilsson,Theocharis Panaretakis +13 more
TL;DR: Exosomes derived from DU145 Tax-Res cells may be a valuable source of biomarkers for response to therapy and show properties of increased matrix degradation in cells that have uptaken DU145tax-Res exosomes.
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Effect of acute exercise on prostate cancer cell growth.
Helene Rundqvist,Martin Augsten,Anna Strömberg,Eric Rullman,Sara Mijwel,Pedram Kharaziha,Theocharis Panaretakis,Thomas Gustafsson,Arne Östman +8 more
TL;DR: It is shown that even the short-term effects seem to add to the overall beneficial influence of exercise on neoplasia, despite the fear of possible detrimental effects of acute exercise serum on tumor cell growth.
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Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies.
TL;DR: Inhibition of autophagy by siRNA-mediated silencing of Beclin 1, as well as chemical inhibition of type III PtdIns3K, inhibits apoptosis, demonstrating an important role of autophileagy in dexamethasone-induced cell death.