P
Peifen Zhang
Researcher at Zhejiang University
Publications - 11
Citations - 285
Peifen Zhang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Microbiome & Gut–brain axis. The author has an hindex of 3, co-authored 11 publications receiving 65 citations.
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Journal ArticleDOI
Fractional amplitude of low frequency fluctuation in drug-naïve first-episode patients with anorexia nervosa: A resting-state fMRI study.
Jianbo Lai,Tingting Xu,Haorong Zhang,Caixi Xi,Hetong Zhou,Yanli Du,Jiajun Jiang,Lingling Wu,Peifen Zhang,Yi Xu,Shaohua Hu,Dongrong Xu +11 more
TL;DR: It is suggested that spontaneous brain activity in the frontal region, hippocampus and rectus, characterized by fALFF values, was altered in drug-naïve, first-episode female patients with AN.
Journal ArticleDOI
Vortioxetine improves rapid eye movement sleep behavior disorder: A case report.
Yanli Du,Jiajun Jiang,Chee H. Ng,Lingling Wu,Peifen Zhang,Caixi Xi,Jianbo Lai,Yi Xu,Shaohua Hu,Zheng Wang +9 more
TL;DR: This is the first reported case of effective treatment of RBD with vortioxetine, and well-designed studies with large samples are needed to verify the clinical benefits.
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Impaired blood-brain barrier in the microbiota-gut-brain axis: Potential role of bipolar susceptibility gene TRANK1
Lai Jianbo,Jiajun Jiang,Peifen Zhang,Caixi Xi,Lingling Wu,Xingle Gao,Yaoyang Fu,Danhua Zhang,Yiqing Chen,Huimin Huang,Yiyi Zhu,Hu Shaohua +11 more
TL;DR: In this article, the influence of intestine microbiota on the expression of bipolar gene TRANK1 was studied and it was shown that intestine microbiota-dependent type 1 interferon signalling is sufficient to induce the over-expression of TRANK 1, consequently causing the compromise of BBB integrity and facilitating the entrance of inflammatory mediators into the brain.
Journal ArticleDOI
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction.
Xiaorong Wang,Huimin Huang,Huimin Huang,Yiyi Zhu,Shaoli Li,Peifen Zhang,Jiajun Jiang,Caixi Xi,Lingling Wu,Xingle Gao,Yaoyang Fu,Danhua Zhang,Yiqing Chen,Shaohua Hu,Jianbo Lai +14 more
TL;DR: In this paper, the authors showed that metformin, a classical antidiabetic agent, is capable of alleviating AIMD possibly by regulating the microbiota-gut-brain axis.
Journal ArticleDOI
Involvement of Kynurenine Metabolism in Bipolar Disorder: An Updated Review
Peifen Zhang,Huimin Huang,Xingle Gao,Jiajun Jiang,Caixi Xi,Lingling Wu,Yaoyang Fu,Jianbo Lai,Shaohua Hu +8 more
TL;DR: In this paper, the authors introduce the altered kynurenine (KYN) pathway and describe the immune dysregulation in patients with bipolar disorder, as well as their interactions with the immune system.