P
Peter C. M. Molenaar
Researcher at Queensland University of Technology
Publications - 559
Citations - 22056
Peter C. M. Molenaar is an academic researcher from Queensland University of Technology. The author has contributed to research in topics: Acetylcholine & Myasthenia gravis. The author has an hindex of 72, co-authored 548 publications receiving 20418 citations. Previous affiliations of Peter C. M. Molenaar include Baker IDI Heart and Diabetes Institute & Leiden University.
Papers
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Journal ArticleDOI
Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum
Kafa Walweel,Jiao Li,Peter C. M. Molenaar,Peter C. M. Molenaar,Mohammad S. Imtiaz,Anthony W. Quail,Chris G. dos Remedios,Nicole A. Beard,Angela F. Dulhunty,Dirk F. van Helden,Derek R. Laver +10 more
TL;DR: In this paper, the Ca(2+)- and Mg(2+)-dependent regulation of human RyR2 was recorded in artificial lipid bilayers in the presence of 2 mM ATP.
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Steps to a formal analysis of the cognitive-energetic model of stress and human performance.
TL;DR: In this article, a formal analysis of the cognitive-energetic model conceived of as a stochastic PERT network is presented, which is regarded as a special instance of Grossberg's (1982) functional-differential network.
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Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.
Kafa Walweel,Nieves Gomez-Hurtado,Robyn T. Rebbeck,Ye Wint Oo,Nicole A. Beard,Peter C. M. Molenaar,Peter C. M. Molenaar,Cris dos Remedios,Dirk F. van Helden,Razvan L. Cornea,Bjorn C. Knollmann,Derek R. Laver +11 more
TL;DR: In this paper, the authors used FRET between donor-FKBP12.6 and acceptor-CaM bound to RyR2 and determined that CaM's biological action on human ryanodine receptor calcium release channels appears to be more nuanced, with inhibitory activity only on phosphorylated channels, which occurs during exercise or in patients with heart failure.
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Autoantibodies to neurotransmitter receptors and ion channels: from neuromuscular to neuropsychiatric disorders.
Pilar Martinez-Martinez,Peter C. M. Molenaar,Mario Losen,Jo Stevens,Marc H. De Baets,Andrei Szöke,Andrei Szöke,Jérôme Honnorat,Ryad Tamouza,Marion Leboyer,Jim van Os,Bart P. F. Rutten +11 more
TL;DR: The pathophysiology of channelopathies of the neuromuscular junction is presented in terms of loss-of-function and gain- of-function principles, which have implications for research and practice.
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A genetic perspective on the developing brain: electrophysiological indices of neural functioning in young and adolescent twins
G.C.M. van Baal,C.E.M. van Beijsterveldt,Peter C. M. Molenaar,Dorret I. Boomsma,E.J.C. de Geus +4 more
TL;DR: In this paper, changes in genetic and environmental influences on electroencephalographic (EEG) and event-related potential (ERP) indices of neural development were studied in two large cohorts of young (n = 418) and adolescent (N = 426) twins.