P
Peter Klepsatel
Researcher at Slovak Academy of Sciences
Publications - 20
Citations - 830
Peter Klepsatel is an academic researcher from Slovak Academy of Sciences. The author has contributed to research in topics: Drosophila melanogaster & Adipokinetic hormone. The author has an hindex of 12, co-authored 18 publications receiving 610 citations. Previous affiliations of Peter Klepsatel include Max Planck Society & University of Veterinary Medicine Vienna.
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Journal ArticleDOI
Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants.
Martina Gáliková,Max Diesner,Peter Klepsatel,Philip Hehlert,Yanjun Xu,Iris Bickmeyer,Reinhard Predel,Ronald P. Kühnlein +7 more
TL;DR: CRISPR/Cas9-mediated genome engineering is employed to create AKH and AKH plus APRP-specific mutants in the model insect Drosophila melanogaster to provide evidence for a negative autoregulatory loop in Akh gene regulation.
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Thermal stress depletes energy reserves in Drosophila
TL;DR: Functional analyses revealed that an intact heat-shock response is essential to protect flies from temperature-dependent body fat decline, and evidence is provided that thermal stress has a significant negative impact on organismal energy reserves, which in turn might affect individual fitness.
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Variation in thermal performance and reaction norms among populations of Drosophila melanogaster.
Peter Klepsatel,Martina Gáliková,Nicola De Maio,Christian D. Huber,Christian Schlötterer,Thomas Flatt +5 more
TL;DR: The results suggest that thermal adaptation in D. melanogaster predominantly involves evolutionary changes in absolute trait values rather than in aspects of thermal reaction norms, which are remarkably similar among different populations.
Journal ArticleDOI
Obesity and Aging in the Drosophila Model
Martina Gáliková,Peter Klepsatel +1 more
TL;DR: The mechanisms that underlie the differential lifespans in distinct types of obesity remain to be elucidated, but fat turnover, inflammatory pathways, and dysregulations of glucose metabolism may play key roles.
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Similarities and differences in altitudinal versus latitudinal variation for morphological traits in drosophila melanogaster
TL;DR: Examining clinal, likely genetically based variation in morphology among 19 populations of the fruit fly from Africa and Europe, spanning a range from sea level to 3000 m altitude and including locations approximating the southern and northern range limit, provides compelling evidence for profound similarities as well as differences between phenotypic effects of latitude and altitude.