P
Peter L Barrett
Researcher at Harvard University
Publications - 3
Citations - 507
Peter L Barrett is an academic researcher from Harvard University. The author has contributed to research in topics: Gene & Gene conversion. The author has an hindex of 3, co-authored 3 publications receiving 486 citations.
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Journal ArticleDOI
Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection
Michael Farzan,Hyeryun Choe,Kathleen A. Martin,Luisa Marcon,Wolfgang Hofmann,Gunilla B. Karlsson,Ying Sun,Peter L Barrett,Nathalie E Marchand,Nancy Sullivan,Norma P. Gerard,Craig Gerard,Joseph Sodroski +12 more
TL;DR: Two orphan seven-transmembrane segment receptors, gpr1 and gpr15, serve as coreceptors for SIV, and are expressed in human alveolar macrophages, and may contribute to an understanding of viral variation and pathogenesis.
Journal ArticleDOI
Lumen Morphogenesis in C. elegans Requires the Membrane-Cytoskeleton Linker erm-1
TL;DR: It is shown that erm-1 is a unique C. elegans ortholog of the ERM family of cytoskeleton-membrane linkers, with an essential role in lumen morphogenesis, and that act-5/cytoplasmic actin and sma-1/beta-H-spectrin are required for lumen formation and functionally interact with erm -1.
Journal ArticleDOI
Targeted gene alteration in Caenorhabditis elegans by gene conversion.
TL;DR: A method to create mutations in the Caenorhabditis elegans genome efficiently through transgene-directed, transposon-mediated gene conversion and an engineered green fluorescent protein insertion-replacement cassette is targeted, thereby confirming that custom alleles of different types can be created in vitro to make the corresponding mutations in vivo.