P
Phei Er Saw
Researcher at Sun Yat-sen University
Publications - 98
Citations - 4110
Phei Er Saw is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 27, co-authored 72 publications receiving 2492 citations. Previous affiliations of Phei Er Saw include Brigham and Women's Hospital & KAIST.
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Journal ArticleDOI
Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy
Wei Tao,Xiaoyuan Ji,Xiaoyuan Ji,Xiao-Ding Xu,Mohammad Ariful Islam,Zhongjun Li,Si Chen,Phei Er Saw,Han Zhang,Zameer Bharwani,Zilei Guo,Jinjun Shi,Omid C. Farokhzad,Omid C. Farokhzad +13 more
TL;DR: A new generation of PTAs based on two-dimensional (2D) antimonene quantum dots (AMQDs) was developed by a novel liquid exfoliation method that demonstrated notable NIR-induced tumor ablation ability and biocompatibility and stability in physiological medium.
Journal ArticleDOI
ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy.
Xiao-Ding Xu,Phei Er Saw,Wei Tao,Yujing Li,Xiaoyuan Ji,Sushant Bhasin,Yanlan Liu,Dana Ayyash,Jonathan Rasmussen,Marc Huo,Jinjun Shi,Omid C. Farokhzad,Omid C. Farokhzad +12 more
TL;DR: An innovative reactive oxygen species (ROS)‐responsive polyprodrug is reported that can self‐assemble into stable NPs with high drug loading that show significant inhibition of tumor cell growth both in vitro and in vivo.
Journal ArticleDOI
Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics.
Wei Tao,Xiaoyuan Ji,Xiaoyuan Ji,Xianbing Zhu,Li Li,Junqing Wang,Ye Zhang,Phei Er Saw,Wenliang Li,Na Kong,Na Kong,Mohammad Ariful Islam,Tian Gan,Xiaowei Zeng,Han Zhang,Morteza Mahmoudi,Guillermo J. Tearney,Omid C. Farokhzad +17 more
TL;DR: A novel photonic drug‐delivery platform based on 2D PEGylated AM nanosheets (NSs) is developed, addressing several key limitations of cancer nanomedicines and marking an exciting jumping‐off point for research into the application of 2D AM nanomaterials in cancer theranostics.
Journal ArticleDOI
Multifunctional Envelope-Type siRNA Delivery Nanoparticle Platform for Prostate Cancer Therapy
Xiao-Ding Xu,Jun Wu,Yanlan Liu,Phei Er Saw,Wei Tao,Mi Kyung Yu,Harshal Zope,Michelle Si,Amanda Victorious,Jonathan Rasmussen,Dana Ayyash,Omid C. Farokhzad,Omid C. Farokhzad,Jinjun Shi +13 more
TL;DR: Systemic delivery of the siRNA NPs can efficiently silence the expression of prohibitin 1 (PHB1), which is upregulated in PCa and other cancers, and significantly inhibit PCa tumor growth.
Journal ArticleDOI
siRNA therapeutics: a clinical reality.
Phei Er Saw,Erwei Song +1 more
TL;DR: This work highlights the breakthroughs in siRNA therapeutics, with special feature on the first FDA approved RNAi therapeutics Onpattro (Patisiran) and the consideration of effective siRNA delivery system focusing on current siRNA nanocarrier in clinical trials.