P
Philip L. Fuchs
Researcher at Purdue University
Publications - 319
Citations - 6425
Philip L. Fuchs is an academic researcher from Purdue University. The author has contributed to research in topics: Sulfone & Cephalostatin. The author has an hindex of 40, co-authored 319 publications receiving 6220 citations. Previous affiliations of Philip L. Fuchs include University of East Anglia.
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Journal ArticleDOI
Spiroketal equilibration : interconversion of 1,6-dioxaspiro[4.4]nonanes and 1,6-dioxaspiro[4.5]decanes. Implications for the synthesis of cephalostatin 7
Jae Uk Jeong,Philip L. Fuchs +1 more
TL;DR: In this paper, an acid-catalyzed equilibration of spiroketals 55H ββ and 55H αβ involves a two-stage process whereby the 1,6-dioxaspiro[4.4]nonanes can be equilibrated under mild conditions to a pair of 1.5-decanes with preservation of the adjacent C-20 methyl stereocenter.
Journal ArticleDOI
Concurrent ring opening and halogenation of spiroketals
Thomas G. LaCour,Philip L. Fuchs +1 more
TL;DR: Ring opening of various spiroketals with triphenylphosphine dihalides under neutral conditions produced ω-halo-enolethers in good yield.
Journal ArticleDOI
Addition of .gamma.-Methoxy Allylsulfonyl Anions to Cyclopentenyl Phenyl Sulfones. A Facile Synthesis of .beta.-Cyclopentenyl-Substituted Dienones and Trienones
Zhendong Jin,Philip L. Fuchs +1 more
Journal ArticleDOI
An Improved Procedure for the Synthesis of 4-Oxopimelate-Derived Materials.1
TL;DR: In the course of one of our synthetic projects as mentioned in this paper, we required efficient access to 4-ethylenedioxy-2-carbomethoxycyclohexanone 6, which has been traditionally accomplished by conversion of 2-furaldehyde 1 to furylacrylic acid 2 via an organic synthesis procedure (90%), followed by treatment of 2 with methanolic HCI to afford dimethyl 4-oxopimelate 3 in reported yields of 60%4 and 80%.