P
Philip Winn
Researcher at Strathclyde Institute of Pharmacy and Biomedical Sciences
Publications - 93
Citations - 4262
Philip Winn is an academic researcher from Strathclyde Institute of Pharmacy and Biomedical Sciences. The author has contributed to research in topics: Pedunculopontine Tegmental Nucleus & Nucleus accumbens. The author has an hindex of 36, co-authored 93 publications receiving 4126 citations. Previous affiliations of Philip Winn include Charing Cross Hospital & University of Hull.
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Journal ArticleDOI
The pedunculopontine tegmental nucleus: where the striatum meets the reticular formation.
Wendy L. Inglis,Philip Winn +1 more
TL;DR: The review indicates that the PPTg is less concerned with the induction of locomotion and more concerned with relating reinforcement with motor output from the dorsal striatum, and forms a 'subsidiary circuit', returning information to striatal circuitry.
Journal ArticleDOI
Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats
Charles D. Blaha,Laura F. Allen,Sheela Das,Wendy L. Inglis,Mary P. Latimer,Steven R. Vincent,Philip Winn,Philip Winn +7 more
TL;DR: The present data show that cholinergic neurons in the LDTg, but not the PPTg, regulate the activity of DA-containing neuron in the VTA, which complements previous data showing that cholinesterase inhibitors in the PTTg regulate DA- containing neurons inThe SNc.
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How best to consider the structure and function of the pedunculopontine tegmental nucleus: Evidence from animal studies
TL;DR: Assessment of the location, composition and connections of the pedunculopontine tegmental nucleus is made to support the hypothesis that it has structural similarities with substantia nigra, suggesting functional similarities exist also.
Journal ArticleDOI
Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats
Charles D. Blaha,Philip Winn +1 more
TL;DR: The data suggest that PPTg cholinergic neurons are indirectly involved in regulating the activity of the striatum by modulating theActivity of DA neurons in the substantia nigra of the rat.
Journal ArticleDOI
Cholinergic modulation of midbrain dopaminergic systems
TL;DR: Brainstem cholinergic neurons are in a position to critically influence the activity of dopaminergic neurons in the midbrain, and thereby have a critical role in the expression of behavior.