P
Philippe Haas
Researcher at French Institute of Health and Medical Research
Publications - 7
Citations - 530
Philippe Haas is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 6, co-authored 7 publications receiving 489 citations. Previous affiliations of Philippe Haas include University of Paris & Paris Diderot University.
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Journal ArticleDOI
Activating KIR genes are associated with CMV reactivation and survival after non-T-cell depleted HLA-identical sibling bone marrow transplantation for malignant disorders
C Chen,Marc Busson,V. Rocha,M-L Appert,Virginia Lepage,Nicolas Dulphy,Philippe Haas,Gérard Socié,Antoine Toubert,Dominique Charron,Pascale Loiseau +10 more
TL;DR: The impact of donor-activating KIR genes on TRM, overall survival and CMV reactivation in HLA-identical sibling HSCT is highlighted.
Journal ArticleDOI
An Unusual CD56brightCD16low NK Cell Subset Dominates the Early Posttransplant Period following HLA-Matched Hematopoietic Stem Cell Transplantation
Nicolas Dulphy,Nicolas Dulphy,Philippe Haas,Marc Busson,Stéphanie Belhadj,Régis Peffault de Latour,Marie Robin,Maryvonnick Carmagnat,Pascale Loiseau,Pascale Loiseau,Ryad Tamouza,Catherine Scieux,Claire Rabian,Claire Rabian,James P. Di Santo,James P. Di Santo,Dominique Charron,Dominique Charron,Anne Janin,Anne Janin,Gérard Socié,Antoine Toubert,Antoine Toubert +22 more
TL;DR: Functional interactions between this subset and T cells may be important in shaping the immune response after HSCT, and IL-15, the levels of which were increased in the posttranplant period, is a major candidate to mediate these changes.
Journal ArticleDOI
MICA-129 genotype, soluble MICA, and anti-MICA antibodies as biomarkers of chronic graft-versus-host disease
Wahid Boukouaci,Marc Busson,Régis Peffault de Latour,Vanderson Rocha,Caroline Suberbielle,Djaouida Bengoufa,Nicolas Dulphy,Philippe Haas,Catherine Scieux,Habiba Amroun,Eliane Gluckman,Rajagopal Krishnamoorthy,Antoine Toubert,Dominique Charron,Gérard Socié,Ryad Tamouza +15 more
TL;DR: Data suggest that the studied MICA genotype and phenotype specificities could be used as relevant biomarkers for cGVHD monitoring.
Journal ArticleDOI
NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation
Philippe Haas,Pascale Loiseau,Ryad Tamouza,Jean-Michel Cayuela,Hélène Moins-Teisserenc,Hélène Moins-Teisserenc,Marc Busson,Marc Busson,Guylaine Henry,Christine S. Falk,Dominique Charron,Dominique Charron,Gérard Socié,Antoine Toubert,Antoine Toubert,Nicolas Dulphy,Nicolas Dulphy +16 more
TL;DR: This donor-ligand-driven NK-cell education model would suggest a sustained graft-versus-leukemia effect after HLA-mismatched HSCT, and suggest that the NK cell's education partner could be of hematopoietic rather than extrahematopoetic origin.
Journal ArticleDOI
Oxidative Stress Mediates a Reduced Expression of the Activating Receptor NKG2D in NK Cells from End-Stage Renal Disease Patients
Marie-Noëlle Peraldi,Jeannig Berrou,Jeannig Berrou,Nicolas Dulphy,Nicolas Dulphy,Alexandre Seidowsky,Philippe Haas,Philippe Haas,Nicolas Boissel,Fabien Metivier,Christine Randoux,Niloufar Kossari,Alain P. Guerin,Sylvie Geffroy,Guy Delavaud,Viviana Marin-Esteban,Denis Glotz,Dominique Charron,Dominique Charron,Antoine Toubert,Antoine Toubert +20 more
TL;DR: Two studies suggest for the first time that both low NKG2D expression and up-regulation of its ligand MICA are related to ROS production and may be involved in the immune deficiency of ESRD patients.