P
Phuong Ngo-Hazelett
Researcher at University of Oregon
Publications - 5
Citations - 1358
Phuong Ngo-Hazelett is an academic researcher from University of Oregon. The author has contributed to research in topics: Zebrafish & Genome. The author has an hindex of 5, co-authored 5 publications receiving 1299 citations. Previous affiliations of Phuong Ngo-Hazelett include University of Michigan.
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Journal ArticleDOI
Zebrafish Comparative Genomics and the Origins of Vertebrate Chromosomes
John H. Postlethwait,Ian G. Woods,Phuong Ngo-Hazelett,Yi-Lin Yan,Peter D. Kelly,Felicia Chu,Hui Huang,Alicia Hill-Force,William S. Talbot +8 more
TL;DR: Comparative analysis suggests that an excess of chromosome fissions in the tetrapod lineage may account for chromosome numbers and provides histories for several human chromosomes.
Journal ArticleDOI
A Comparative Map of the Zebrafish Genome
Ian G. Woods,Peter D. Kelly,Felicia Chu,Phuong Ngo-Hazelett,Yi-Lin Yan,Hui Huang,John H. Postlethwait,William S. Talbot +7 more
TL;DR: A homozygous diploid meiotic mapping panel is used to localize polymorphisms in 691 previously unmapped genes and expressed sequence tags (ESTs) and to enhance the understanding of the evolution of the vertebrate genome.
Journal ArticleDOI
Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development.
Junya Masumoto,Weibin Zhou,Felicia F. Chen,Fengyun Su,John Y. Kuwada,Eiko Hidaka,Tsutomu Katsuyama,Junji Sagara,Shun'ichiro Taniguchi,Phuong Ngo-Hazelett,John H. Postlethwait,Gabriel Núñez,Naohiro Inohara +12 more
TL;DR: These studies suggest that zAsc mediates the activation of Caspy, a caspase that plays an important role in the morphogenesis of the jaw and gill-bearing arches.
Journal ArticleDOI
Genetic linkage mapping of zebrafish genes and ESTs.
Peter D. Kelly,Felicia Chu,Ian G. Woods,Phuong Ngo-Hazelett,Timothy Cardozo,Hui Huang,Frankie Kimm,Lingya Liao,Yi-Lin Yan,Yingyao Zhou,Steven L. Johnson,Ruben Abagyan,Alexander F. Schier,John H. Postlethwait,William S. Talbot +14 more
TL;DR: A genetic linkage map that will facilitate the identification of candidate genes for these mutations and allow comparisons among the genomes of zebrafish and other vertebrates is constructed.
Journal ArticleDOI
Conserved function of caspase-8 in apoptosis during bony fish evolution.
Shin-ichi Sakata,Yi-Lin Yan,Yutaka Satou,Akihiro Momoi,Phuong Ngo-Hazelett,Masami Nozaki,Makoto Furutani-Seiki,John H. Postlethwait,Shin Yonehara,Kazuhiro Sakamaki +9 more
TL;DR: The results show that zebrafish casp8 has a structure and function similar to mammalian CASP8 orthologs, and this study suggests that the role of caspase-8 in the apoptotic signal pathway has been conserved over at least 450 million years of vertebrate evolution.