P
Pierre Ernst
Researcher at McGill University
Publications - 241
Citations - 17884
Pierre Ernst is an academic researcher from McGill University. The author has contributed to research in topics: Asthma & COPD. The author has an hindex of 64, co-authored 232 publications receiving 16614 citations. Previous affiliations of Pierre Ernst include Jewish General Hospital & McGill University Health Centre.
Papers
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Journal ArticleDOI
The Use of β-Agonists and the Risk of Death and near Death from Asthma
W O Spitzer,Samy Suissa,Pierre Ernst,Ralph I. Horwitz,Brian F. Habbick,Donald W. Cockcroft,Jean-Francois Boivin,M McNutt,A S Buist,A. S. Rebuck +9 more
TL;DR: The use ofβ-agonists administered by a metered-dose inhaler was associated with an increased risk of death from asthma and the regular use of β2-agonist bronchodilators.
Journal ArticleDOI
Low-dose inhaled corticosteroids and the prevention of death from asthma.
TL;DR: The regular use of low-dose inhaled corticosteroids is associated with a decreased risk of death from asthma and was higher than the rate among patients who continued to use the drugs.
Journal ArticleDOI
Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma.
Eleanor M. Minshall,Donald Y.M. Leung,Richard J. Martin,Yan Ling Song,Lisa Cameron,Pierre Ernst,Qutayba Hamid +6 more
TL;DR: Evidence is provided that TGF-beta1 may play a role in the fibrotic changes occurring within asthmatic airways and that activated eosinophils are a major source of this cytokine.
Journal ArticleDOI
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality
TL;DR: Two strategic targets for COPD management should include delaying the second severe exacerbation and improving treatment of severe exacerbations to reduce their excessive early mortality.
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Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid
TL;DR: Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid and correlated with pulmonary functions and airway responsiveness.