P
Pierre Monsan
Researcher at Centre national de la recherche scientifique
Publications - 216
Citations - 8592
Pierre Monsan is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Leuconostoc mesenteroides & Dextransucrase. The author has an hindex of 51, co-authored 216 publications receiving 8049 citations. Previous affiliations of Pierre Monsan include Roussel Uclaf & Institut Universitaire de France.
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Journal ArticleDOI
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
Matteo Serino,Elodie Luche,Sandra Grès,Audrey Baylac,Mathieu Bergé,Claire Cenac,Aurélie Waget,Pascale Klopp,Jason S. Iacovoni,Christophe Klopp,Jérôme Mariette,Olivier Bouchez,Jérôme Lluch,Françoise Ouarné,Pierre Monsan,Philippe Valet,Christine Roques,Jacques Amar,Anne Bouloumié,Vassilia Theodorou,Rémy Burcelin +20 more
TL;DR: The HFD-D gut microbial profile was associated with increased gut permeability linked to increased endotoxaemia and to a dramatic increase in cell number in the stroma vascular fraction from visceral white adipose tissue.
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Glucansucrases: mechanism of action and structure–function relationships
TL;DR: In order to synthesise oligosaccharides of biological interest or to develop vaccines against dental caries, elucidation of the factors determining the regiospecificity and the regioselectivity of glucansucrases is necessary.
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Homopolysaccharides from lactic acid bacteria
Pierre Monsan,Sophie Bozonnet,Cécile Albenne,Gilles Joucla,René-Marc Willemot,Magali Remaud-Simeon +5 more
TL;DR: The enzymatic synthesis of fructans (levan and inulin) is poorly documented at the molecular level, but the field of Streptococcus and Leuconostoc glucansucrases (glucosyltransferases and dextransucrase) has been well studied, both at the mechanistic and gene structure levels.
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Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes
Lena Tasse,Juliette Bercovici,Sandra Pizzut-Serin,Patrick Robe,Julien Tap,Christophe Klopp,Brandi L. Cantarel,Pedro M. Coutinho,Bernard Henrissat,Marion Leclerc,Joël Doré,Pierre Monsan,Magali Remaud-Simeon,Gabrielle Potocki-Véronèse +13 more
TL;DR: A multi-step functionally based approach to guide the in-depth pyrosequencing of specific regions of the human gut metagenome encoding the CAZymes involved in dietary fiber breakdown is described, providing new insights into the human Gut functional trophic chain.
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Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family.
Lars K. Skov,Osman Mirza,Anette Henriksen,Gabrielle Potocki De Montalk,Magali Remaud-Simeon,Patricia Sarçabal,René-Marc Willemot,Pierre Monsan,Michael Gajhede +8 more
TL;DR: The structure of amylosucrase from Neisseria polysaccharea is divided into five domains: an all helical N-terminal domain that is not similar to any known fold, a (β/α)8-barrel A-domain, B- and B′-domains displaying α/β-structure, and a C-terminals eight-stranded β-sheet domain.