Showing papers by "Pierre-Vladimir Ennezat published in 2012"
TL;DR: The results suggest an additive value of the study of left ventricular myocardial deformation to classical clinical and echocardiographic variables for the prediction of POAF in this setting is suggested.
37 citations
TL;DR: In this article, the frequency of left heart valve regurgitations in diabetic patients exposed to benfluorex for at least 3 months and in diabetic control subjects never exposed to the drug was compared.
Abstract: Background—Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions. The link between benfluorex and valve regurgitations was based on small observational studies and retrospective estimations. We therefore designed an echocardiography-based multicenter study to compare the frequency of left heart valve regurgitations in diabetic patients exposed to benfluorex for at least 3 months and in diabetic control subjects never exposed to the drug. Methods and Results—This reader-blinded, controlled study conducted in 10 centers in France between February 2010 and September 2011 prospectively included 376 diabetic subjects previously exposed to benfluorex who were referred by primary care physicians for echocardiography and 376 diabetic control subjects. Through the use of propensity scores, 293 patients and 293 control subjects were matched for age, sex, body mass index, smoking, dyslipidemia, hypertension, and coronary artery disease. The main outcome ...
28 citations
TL;DR: The use of central extracorporeal life support (ECLS) was used to treat pheochromocytoma-induced cardiogenic shock complicated by pulmonary edema in a young woman admitted to the intensive care unit with cardiogenesis shock.
20 citations
TL;DR: Longitudinal 2D-speckle-tracking data accurately match with endocardial mapping findings for localizing atrioventricular accessory pathways and identifies persistence of local ventricular pre-excitation immediately after successful ablation.
Abstract: Aims The present study was undertaken to investigate the concordance between longitudinal two-dimensional (2D)-speckle-tracking data and endocardial mapping for localizing atrioventricular accessory pathways (AP), and whether longitudinal 2D-speckle-tracking imaging accurately identifies the contractile abnormalities associated with AP and the effect of radiofrequency ablation.
Methods and results Echocardiograms were repeated twice in 40 patients with Wolff–Parkinson–White (WPW) syndrome (before and early after ablation) and in 40 healthy controls to obtain longitudinal 2D strain and strain rate data. The site of ablation was considered as the gold standard for the AP localization. While control patients had a homogeneous strain pattern, all but two patients with WPW had an abnormal deformation pattern with three peaks in one or two basal contiguous segments: an early peak concomitantly with the delta wave followed by a systolic and a post-sytolic one. The rapid increase in LV longitudinal deformation within the basal pre-excited zone resulted in a pre-systolic peak strain rate at the beginning of the delta wave by SR imaging that was not found in controls. The early basal contraction spread towards the mid-ventricle before merging with the normal activated segments in 15 patients (39%). Contractile abnormalities were no more than one adjacent segment different compared with the AP ablation site in all these 38 patients. Regional strain was impaired in the pre-excited areas especially in AP localized in the interventricular septum. The abnormal deformation pattern persisted in 16 (42%) patients despite successful radiofrequency ablation. However, the difference in the regional strain between WPW patients and controls did not remain after ablation.
Conclusion Longitudinal 2D-speckle-tracking data accurately match with endocardial mapping findings for localizing AP. Longitudinal 2D-speckle-tracking imaging accurately identifies AP-associated contractile abnormalities. Longitudinal 2D-speckle-tracking identifies persistence of local ventricular pre-excitation immediately after successful ablation.
13 citations
TL;DR: A 54-year-old obese woman with a history of hypertension dialed ambulance service for headache and vomiting and was transferred in the intensive care unit.
Abstract: A 54-year-old obese woman with a history of hypertension dialed ambulance service for headache and vomiting. EKG found diffuse ST segment elevation (figure 1A). Prehospital management consisted of intravenous aspirin, oral antiplatelet therapy (prasugrel) and subcutaneous low-molecular-weight heparin. She was transferred in our intensive care unit. Echocardiography showed impaired left ventricular ejection fraction (30%) with apical dysfunction but preserved basal function (figure 1B–D). Coronary angiography showed normal epicardial coronary arteries (figure 1E,F …
6 citations
5 citations
TL;DR: Chopard et al. as mentioned in this paper found that 10% of patients with suspected acute coronary syndrome (ACS) but normal coronary arteries and absence of abnormality on cardiac magnetic resonance imaging (MRI) are close to zero.