Pietro Arina

TL;DR: In this article, the authors identified two randomised controlled trials and 83 observational studies, compromising 13,931 patients, that examined the effects of NIRS modalities on patients with COVID-19-associated acute respiratory failure.

TL;DR: The role of cholesterol and derivatives molecules in breast cancer development is still controversial, but the use of cholesterol targeting drugs like statins and zoledronic acid appears as a challenging promising tool for breast cancer treatment.

TL;DR: In this paper , a literature search was performed to identify relevant articles, particularly those pertinent to unclear diagnoses in patients who are critically ill. The aim of this narrative review is to analyse and describe common causes of diagnostic error in the intensive care unit, highlighting the multiple types of cognitive bias, and to suggest a diagnostic framework.

TL;DR: In this article , a systematic review and meta-analysis of published studies on PubMed and Embase was conducted to ascertain the association between cholesterol and triglyceride levels on ICU admission and mortality in patients with sepsis.

TL;DR: In this article , the authors analyze the mechanisms by which the tumor microenvironment affects the characteristics of tumor heterogeneity that ultimately result in drug resistance, and outline state of the art preclinical models and emerging technologies that will be instrumental in unraveling the impact of tumor micro-environment on resistance to therapies.