P
Piper Reid Hunt
Researcher at Center for Food Safety and Applied Nutrition
Publications - 14
Citations - 754
Piper Reid Hunt is an academic researcher from Center for Food Safety and Applied Nutrition. The author has contributed to research in topics: Caenorhabditis elegans & Toxicity. The author has an hindex of 9, co-authored 12 publications receiving 580 citations. Previous affiliations of Piper Reid Hunt include Johns Hopkins University School of Medicine & Children's Hospital of Philadelphia.
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Journal ArticleDOI
The C. elegans model in toxicity testing.
TL;DR: The case for inclusion of C. elegans assays in early safety testing and as one component in tiered or integrated toxicity testing strategies is made, but results do not indicate that nematodes alone can replace data from mammals for hazard evaluation.
Journal ArticleDOI
Extension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms
Piper Reid Hunt,Tae Gen Son,Mark A. Wilson,Quian Sheng Yu,William H. Wood,Yongqing Zhang,Kevin G. Becker,Nigel H. Greig,Mark P. Mattson,Simonetta Camandola,Catherine A. Wolkow +10 more
TL;DR: The findings reveal the potential for low doses of naturally occurring naphthoquinones to extend lifespan by engaging a specific adaptive cellular stress response pathway.
Journal ArticleDOI
Deletions of 20p12 in Alagille syndrome: Frequency and molecular characterization
Ian D. Krantz,Elizabeth B. Rand,Anna Genin,Piper Reid Hunt,Marilyn C. Jones,Anthonise A. Louis,John M. Graham,Sucheta Bhatt,David A. Piccoli,Nancy B. Spinner +9 more
TL;DR: The frequency of deletions observed in contiguous gene deletion syndromes suggesting that Alagille syndrome may be caused by the alteration of a single gene is considerably lower than the frequency of deleting in contiguous genes in contiguous syndrome.
Journal ArticleDOI
Toxicity ranking of heavy metals with screening method using adult Caenorhabditis elegans and propidium iodide replicates toxicity ranking in rat
TL;DR: It was found that chronic toxicity assays of 2-week treatment duration, followed by analysis of PI induced red fluorescence levels, produced less consistent results than the acute assays, however, other chronic toxicity endpoints were compound and concentration specific.
Journal ArticleDOI
Nanosilver suppresses growth and induces oxidative damage to DNA in Caenorhabditis elegans
Piper Reid Hunt,Bryce J. Marquis,Katherine M. Tyner,Sean D. Conklin,Nicholas Olejnik,Bryant C. Nelson,Robert L. Sprando +6 more
TL;DR: In this paper, the utility of Caenorhabditis elegans cultured in axenic liquid media was evaluated as an alternative in vivo model for the purpose of screening nanomaterials for toxic effects.