P
Pratap Challa
Researcher at Duke University
Publications - 115
Citations - 3460
Pratap Challa is an academic researcher from Duke University. The author has contributed to research in topics: Glaucoma & Intraocular pressure. The author has an hindex of 32, co-authored 109 publications receiving 2968 citations. Previous affiliations of Pratap Challa include University of Erlangen-Nuremberg & Durham University.
Papers
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Journal ArticleDOI
VEGF as a Paracrine Regulator of Conventional Outflow Facility.
Ester Reina-Torres,Joanne C Wen,Katy C. Liu,Guorong Li,Joseph M. Sherwood,Jason Y. Chang,Pratap Challa,Cassandra Flügel-Koch,W. Daniel Stamer,R. Rand Allingham,Darryl R. Overby +10 more
TL;DR: VEGF is a paracrine regulator of conventional outflow facility that is secreted by TM cells in response to mechanical stress, and disruption of VEGF signaling in the TM may explain why anti-VEGF therapy is associated with decreased out flow facility and sustained ocular hypertension.
Journal ArticleDOI
Survey of glaucoma in an eye clinic in Ghana, West Africa.
Leon W. Herndon,Pratap Challa,Ben Ababio-Danso,John O. Boateng,Bob Broomer,Philip Ridenhour,R. Rand Allingham +6 more
TL;DR: Primary open-angle glaucoma is the most common form of glau coma being treated in this outpatient eye clinic in Ghana and was usually undiagnosed due to a lack of gonioscopic evaluation.
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Protective Effects of Resveratrol in Experimental Retinal Detachment
TL;DR: In this paper, resveratrol, a potent antioxidant and small molecule activator of the FoxO pathway, was found to be neuroprotective against photoreceptor cell death in a rodent model of retinal detachment.
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Correlation among retinal thickness, optic disc, and visual field in glaucoma patients and suspects: a pilot study.
Sanjay Asrani,Pratap Challa,Leon W. Herndon,Paul P. Lee,Sandra S. Stinnett,R. Rand Allingham +5 more
TL;DR: Retinal thickness measurements at the posterior pole provide another measure of neural loss in glaucoma, and may help in the clinical assessment of optic nerve cupping, however, there are limitations of the technology that must be considered.
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Exposure of Ex-PRESS Miniature Glaucoma Devices: case series and technique for tube shunt removal.
TL;DR: As an increasing number of patients undergo filtration surgery with Ex-PRESS Miniature Glaucoma Devices, anterior segment surgeons should be aware of the potential for device exposure and methods for device removal.