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Priyalakshmi Viswanathan
Researcher at King's College London
Publications - 18
Citations - 730
Priyalakshmi Viswanathan is an academic researcher from King's College London. The author has contributed to research in topics: Cellular differentiation & Stem cell. The author has an hindex of 12, co-authored 18 publications receiving 570 citations. Previous affiliations of Priyalakshmi Viswanathan include University of Sheffield.
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Journal ArticleDOI
3D Surface Topology Guides Stem Cell Adhesion and Differentiation
Priyalakshmi Viswanathan,Matthew G. Ondeck,Somyot Chirasatitsin,Kamolchanok Ngamkham,Gwendolen C. Reilly,Adam J. Engler,Giuseppe Battaglia +6 more
TL;DR: It is demonstrated that the adhesive heterogeneity of a 3D scaffold could regulate not only mesenchymal stem cell attachment but also cell behavior in the absence of soluble growth factors.
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A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells
Gernot Walko,Samuel Woodhouse,Angela Oliveira Pisco,Emanuel Rognoni,Kifayathullah Liakath-Ali,Beate M. Lichtenberger,Ajay Kumar Mishra,Stephanie B. Telerman,Priyalakshmi Viswanathan,Meike E. W. Logtenberg,Lisa M. Renz,Giacomo Donati,Sven R Quist,Fiona M. Watt +13 more
TL;DR: It is proposed that defective intercellular adhesion contributes to uncontrolled cSCC growth by preventing inhibition of YAP/WBP2, and YAP and WPB2 are upregulated in actively proliferating cells of mouse and human epidermis and cS CC, and downregulated during terminal differentiation.
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3D Surface Functionalization of Emulsion-Templated Polymeric Foams
Priyalakshmi Viswanathan,David W. Johnson,Claire R. Hurley,Neil R. Cameron,Giuseppe Battaglia +4 more
TL;DR: In this article, the authors describe the preparation of porous polymeric scaffolds via polymerization of the oil phase in high internal phase water-in-oil-emulsions using amphiphilic block copolymers.
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Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells.
Andreas Reimer,Aliaksei Vasilevich,Frits Hulshof,Priyalakshmi Viswanathan,Clemens van Blitterswijk,Jan de Boer,Fiona M. Watt +6 more
TL;DR: Small feature size was the most important determinant of pluripotency, followed by high wave number and high feature density, and this approach facilitates the design of substrates for optimal human iPSC expansion, but also, potentially, identification of topographies with other desirable characteristics, such as promoting differentiation.
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Cell Instructive Microporous Scaffolds Through Interface Engineering
Priyalakshmi Viswanathan,Somyot Chirasatitsin,Kamolchanok Ngamkham,Adam J. Engler,Giuseppe Battaglia +4 more
TL;DR: The synthesis and characterization of porous foams prepared by high internal phase emulsion (HIPE) templating using amphiphilic copolymers that act as surfactants during the HIPE process are reported.