P
Priyanka Shah
Researcher at Central Drug Research Institute
Publications - 19
Citations - 435
Priyanka Shah is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Docking (molecular) & Quantitative structure–activity relationship. The author has an hindex of 12, co-authored 19 publications receiving 378 citations.
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Journal ArticleDOI
Interaction of a ruthenium(II)–chalcone complex with double stranded DNA: Spectroscopic, molecular docking and nuclease properties
Ruchi Gaur,Rais Ahmad Khan,Sartaj Tabassum,Priyanka Shah,Mohammad Imran Siddiqi,Lallan Mishra +5 more
TL;DR: In this paper, the interaction of a well characterized new complex 1 cis,fac-[RuCl(dmso-S)3(L)] LH = 1-(2-hydroxyphenyl)-3-(4-chlorophenyl) propenone with Calf-thymus DNA (CT-DNA) is monitored using UV-vis titration and ethidium bromide displacement studies.
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Synthesis of hybrid 4-anilinoquinoline triazines as potent antimalarial agents, their in silico modeling and bioevaluation as Plasmodium falciparumtransketolase and β-hematin inhibitors
Moni Sharma,Kuldeep Chauhan,Shikha S. Chauhan,Ashok Kumar,Shiv Vardan Singh,Jitendra Kumar Saxena,Pooja Agarwal,Kumkum Srivastava,S. Raja Kumar,Sunil K. Puri,Priyanka Shah,Mohd Imran Siddiqi,Prem M. S. Chauhan +12 more
TL;DR: Analogues of a novel class of hybrid 4-anilinoquinoline triazines synthesized with the aim of identifying the compounds with improved antimalarial activity preserving the potency of parent drug chloroquine reveal that the molecules are also good inhibitors of the enzyme P. falciparumtransketolase.
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Interaction between sulphur mobilisation proteins SufB and SufC: evidence for an iron-sulphur cluster biogenesis pathway in the apicoplast of Plasmodium falciparum.
Bijay Kumar,Sushma Chaubey,Priyanka Shah,Aiman Tanveer,Manish Charan,Mohammad Imran Siddiqi,Saman Habib +6 more
TL;DR: The ATPase activity of recombinant P. falciparum nuclear-encoded SufC and its localisation in the apicoplast is demonstrated, suggesting the evolution of specialised functions in the plastid counterparts.
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Synthesis, molecular modeling and bio-evaluation of cycloalkyl fused 2-aminopyrimidines as antitubercular and antidiabetic agents
Nimisha Singh,Sarvesh Kumar Pandey,Namrata Anand,Richa Dwivedi,Shyam Singh,Sudhir Sinha,Vinita Chaturvedi,Natasa Jaiswal,Arvind K. Srivastava,Priyanka Shah,M. Imran Siddiqui,Rama Pati Tripathi +11 more
TL;DR: In silico docking studies indicate that mycobacterial dihydrofolate reductase is the possible target of these compounds, and opens a new gate to synthesize antitubercular agents for diabetic TB patients.
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Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.
Koneni V. Sashidhara,Suriya P. Singh,Anuj Srivastava,Anju Puri,Yashpal S. Chhonker,Rabi Sankar Bhatta,Priyanka Shah,Mohammad Imran Siddiqi +7 more
TL;DR: The in vivo effects of 1 corroborated well with its molecular docking analysis and also with its hamster plasma pharmacokinetics, indicating a new structural class of HMG-CoA reductase inhibitor.