Qi Zhang

TL;DR: In this article, a clean green, efficient and facile protocol was developed for the synthesis of a series of 2,3-dihydropyrido[2,3]-pyrimidin-4(1H)-ones in water with good yield by the reaction of 2-amino-nicotinonitriles with carbonyls catalyzed by DBU under microwave irradiation.

TL;DR: A series of multi donor-acceptor substituted pyridine derivative dyes were synthesized by three-component catalyst-free domino reaction in methanol aqueous at room temperature as discussed by the authors.

TL;DR: In this article, a new modification of the Friedlander reaction is described and the new byproduct obtained from the reaction of O-aminonitriles and ketones was found to be 2,3-dihydroquinazolin-4(1 H)-one.

TL;DR: In this article, an efficient synthetic method for the preparation of quinazolin-4-one derivatives was designed, based on the facile condensation of aromatic o-aminonitriles with aromatic aldehydes catalyzed by Lewis acid.

TL;DR: In this article, a modified Friedlander conversion of the cyclocondensation of aromatic o-aminonitriles with carbonyl compounds was discovered, and it was shown that both the new transformation and the classic Friedlander annulation in the presence of ZnCl2 constitute a pair of divergent reaction.