Qinqin Xu

TL;DR: ARGLU1 is established as a new MED1-interacting protein required for estrogen-dependent gene transcription and breast cancer cell growth, as well as anchorage-dependent and -independent colony formation of breast cancer cells.

TL;DR: A novel cell-based phenotypic profiling strategy that uses electronic impedance readouts for real-time monitoring of cellular responses to traditional Chinese medicines (TCMs) and suggests that using TCRP as an alternative to existing spectroscopic techniques can allow us to analyze natural products in a more convenient and physiologically relevant manner.

TL;DR: The data showed that the protein-tyrosine phosphatase SHP2 was involved in the process of EMT and Hook1 repressed EMT by regulating the activation ofSHP2, which suggested that Hook1 was an endogenous negative regulator of SHp2 phosphat enzyme activity.

TL;DR: The notion that the cereblon binding partner AGO2 plays an important role in regulating MM cell growth and survival and AGO 2 could be considered as a novel drug target for overcoming IMiD resistance in MM cells is supported.

TL;DR: In this paper, the authors investigated the cultured mycelia of Cordyceps ophioglossoides and found three unusual spiro[4.5]decane sesquiterpenes, cordycepol A (1), cordycopepla B (2), and cordycerol C (3), and a new fumagillol analogue cordycol (4).