Q
Qiong Li
Researcher at University of North Carolina at Greensboro
Publications - 17
Citations - 1002
Qiong Li is an academic researcher from University of North Carolina at Greensboro. The author has contributed to research in topics: Alcoholic liver disease & Alcoholic fatty liver. The author has an hindex of 15, co-authored 17 publications receiving 815 citations.
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Journal ArticleDOI
A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids
Xiaojiao Zheng,Yunping Qiu,Wei Zhong,Sarah Baxter,Mingming Su,Qiong Li,Guoxiang Xie,Brandon M. Ore,Shanlei Qiao,Melanie D. Spencer,Steven H. Zeisel,Zhanxiang Zhou,Aihua Zhao,Wei Jia,Wei Jia +14 more
TL;DR: A rapid method of simultaneously determining SCFAs and BCAAs in biological samples using propyl chloroformate (PCF) derivatization followed by gas chromatography–mass spectrometry (GC–MS) analysis is reported.
Journal ArticleDOI
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption
Guoxiang Xie,Wei Zhong,Houkai Li,Qiong Li,Yunping Qiu,Xiaojiao Zheng,Huiyuan Chen,Xueqing Zhao,Shucha Zhang,Zhanxiang Zhou,Steven H. Zeisel,Wei Jia +11 more
TL;DR: An improved understanding of the systemic modulations of bile acid metabolism in mammals through the gut‐liver axis is provided.
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Chronic Ethanol Consumption Alters Mammalian Gastrointestinal Content Metabolites
Guoxiang Xie,Wei Zhong,Xiaojiao Zheng,Qiong Li,Yunping Qiu,Houkai Li,Huiyuan Chen,Zhanxiang Zhou,Wei Jia,Wei Jia +9 more
TL;DR: An improved understanding of the systemic alteration of intestinal content metabolites in mammals and the interplay between the host and its complex resident microbiota is provided and may aid in the design of new therapeutic strategies that target these interactions.
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Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice
Wei Zhong,Wenliang Zhang,Qiong Li,Guoxiang Xie,Qian Sun,Xiuhua Sun,Xiaobing Tan,Xinguo Sun,Wei Jia,Zhanxiang Zhou +9 more
TL;DR: Parmacological activation of ALDH2 by Alda-1 reversed alcoholic steatosis and apoptosis through accelerating aldehyde clearance and indicates that AL DH2 is a promising molecular target and Alda -1 has therapeutic potential for treating alcoholic liver disease.
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Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice.
Xiuhua Sun,Yunan Tang,Xiaobing Tan,Qiong Li,Wei Zhong,Xinguo Sun,Wei Jia,Craig J. McClain,Zhanxiang Zhou +8 more
TL;DR: Results demonstrated that activation of PPAR-γ by rosiglitazone reverses ethanol-induced adipose dysfunction and lipid dyshomeostasis at the WAT-liver axis, thereby abrogating alcoholic fatty liver.