Huiyuan Chen

TL;DR: An improved understanding of the systemic modulations of bile acid metabolism in mammals through the gut‐liver axis is provided.

TL;DR: An improved understanding of the systemic alteration of intestinal content metabolites in mammals and the interplay between the host and its complex resident microbiota is provided and may aid in the design of new therapeutic strategies that target these interactions.

TL;DR: This study demonstrates that the metabonomic strategy will enable us to integrate the overwhelming amount of metabolic end points as a systems' response to the absorption, metabolism, and disposition of a multicomponent botanical intervention system, leading to a direct elucidation of their mechanisms of action.

TL;DR: Q3G and Q3GN are bioavailable polyphenols in GE, GP acutely improves glucose tolerance and chronically reduces markers of inflammation in obese mice, and Q 3G reduces several markers ofinflammation in human adipocytes.

TL;DR: An integrated profiling approach is developed that simultaneously captures the entire spectrum of ingredients and quantitatively determines the levels of seven key ingredients in the TCM product and will complement the current quality control standard using the concentration of several key ingredients or their total content.