Q
Quentin Favre-Godal
Researcher at Northeastern University
Publications - 19
Citations - 749
Quentin Favre-Godal is an academic researcher from Northeastern University. The author has contributed to research in topics: Antibiotics & Dendrobium. The author has an hindex of 9, co-authored 16 publications receiving 425 citations. Previous affiliations of Quentin Favre-Godal include University of Lausanne & University of Strasbourg.
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Journal ArticleDOI
A new antibiotic selectively kills Gram-negative pathogens
Yu Imai,Kirsten J. Meyer,Akira Iinishi,Quentin Favre-Godal,Robert Green,Sylvie Manuse,Mariaelena Caboni,Miho Mori,Samantha Niles,Meghan Ghiglieri,Chandrashekhar Honrao,Xiaoyu Ma,Jason J. Guo,Alexandros Makriyannis,Luis Linares-Otoya,Nils Böhringer,Zerlina G. Wuisan,Hundeep Kaur,Runrun Wu,André Mateus,Athanasios Typas,Mikhail M. Savitski,Josh L. Espinoza,Aubrie O'Rourke,Karen E. Nelson,Sebastian Hiller,Nicholas Noinaj,Till F. Schäberle,Till F. Schäberle,Anthony D'Onofrio,Kim Lewis +30 more
TL;DR: Bacterial symbionts of animals may contain antibiotics that are particularly suitable for development into therapeutics; one such compound, darobactin, is active against important Gram-negative pathogens both in vitro and in animal models of infection.
Journal ArticleDOI
Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.
Stéphane Dorsaz,Tiia Snäkä,Quentin Favre-Godal,Pierre Marc Xavier Maudens,Nathalie Boulens,Pascal Furrer,Samad Nejad Ebrahimi,Matthias Hamburger,Eric Allémann,Katia Gindro,Emerson Ferreira Queiroz,Howard Riezman,Jean-Luc Wolfender,Dominique Sanglard +13 more
TL;DR: The results unambiguously identified Erg6, a C-24 sterol methyltransferase absent in mammals, to be the main direct target of tomatidine, a novel antifungal agent targeting Candida albicans systemic infection.
Journal ArticleDOI
Antifungal Quinoline Alkaloids from Waltheria indica
Sylvian Cretton,Stéphane Dorsaz,Antonio Azzollini,Quentin Favre-Godal,Laurence Marcourt,Samad Nejad Ebrahimi,Francine Voinesco,Emilie Michellod,Dominique Sanglard,Katia Gindro,Jean-Luc Wolfender,Muriel Cuendet,Philippe Christen +12 more
TL;DR: The isolated constituents and 10 additional quinoline alkaloids previously isolated from the roots of the plant were evaluated for their in vitro antifungal activity against the human fungal pathogen Candida albicans, and 10 compounds showed growth inhibitory activity on both planktonic cells and biofilms.
Journal ArticleDOI
Orchids and their mycorrhizal fungi: an insufficiently explored relationship
TL;DR: A putative model representing the different molecular strategies that OM fungi might employ to establish this association with arbuscular mycorrhiza is proposed and targeted and untargeted metabolomics studies with special attention to each partner’s contribution are encouraged and some technical approaches are proposed.
Journal ArticleDOI
Comprehensive approach for the detection of antifungal compounds using a susceptible strain of Candida albicans and confirmation of in vivo activity with the Galleria mellonella model
Quentin Favre-Godal,Stéphane Dorsaz,Emerson Ferreira Queiroz,Céline Conan,Laurence Marcourt,Bambang Prajogo Eko Wardojo,Francine Voinesco,Aurélie Buchwalder,Katia Gindro,Dominique Sanglard,Jean-Luc Wolfender +10 more
TL;DR: The overall procedure represents a rational and comprehensive means of evaluating antifungal activity from various perspectives for the selection of initial hits that can be explored in more in-depth mode-of-action studies.