R
R.A. Walters
Researcher at Los Alamos National Laboratory
Publications - 39
Citations - 1642
R.A. Walters is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: Histone & RNA. The author has an hindex of 23, co-authored 39 publications receiving 1632 citations. Previous affiliations of R.A. Walters include Northern Illinois University.
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Cell cycle-specific changes in histone phosphorylation associated with cell proliferation and chromosome condensation.
TL;DR: It is concluded that f1 phosphorylation is one of the earliest biochemical events associated with conversion of nonproliferating cells to proliferating cells occurring on old f1 before synthesis of new f1 during the S phase.
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Effects of Caffeine on Radiation-Induced Phenomena Associated with Cell-Cycle Traverse of Mammalian Cells
TL;DR: Caffeine induced a state of G(1) arrest when added to an exponentially growing culture of Chinese hamster cells (line CHO) and ameliorated a number of the responses of cells to ionizing radiation.
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Cell-cycle-dependent variations of deoxyribonucleoside triphosphate pools in chinese hamster cells
TL;DR: Variation of levels of the four deoxyribonucleoside triphosphate pools has been examined as synchronized Chinese hamster cells complete mitosis and traverse the cell cycle in preparation for division to indicate that Mitotic cells have the largest pools of dATP, dGTP, and dTTP and that all four dexyribon nucleoside Triphosphates are degraded as cells exit from mitosis.
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Histone phosphorylation in late interphase and mitosis
TL;DR: These experiments suggest consideration of the concept that f1 phosphorylation is initiated as a preparation for impending cell division, as it is concluded that f2a2 phosphorylated histone is not dependent on continous DNA replication.
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Evidence that x-irradiation inhibits DNA replicon initiation in Chinese hamster cells.
R.A. Walters,C.E. Hildebrand +1 more
TL;DR: Analysis of DNA replicated 20–30 min after x-irradiation showed that the relative size distribution of single-strand DNA was deficient in DNA 7 daltons and enriched in DNA > 4 × 10 7 dALTons, indicating that x-IRradiation preferentially inhibits replicon initiation, with relatively little effect on elongation.