R. Baron

TL;DR: This second European Federation of Neurological Societies Task Force aimed at updating the existing evidence about the pharmacological treatment of neuropathic pain since 2005.

TL;DR: Somatosensory profiles with different combinations of loss and gain are shared across the major neuropathic pain syndromes, including thermal and mechanical hyperalgesias, which were most frequent in complex regional pain syndrome and peripheral nerve injury, allodynia in postherpetic neuralgia.

TL;DR: The previous EFNS guidelines on neuropathic pain assessment aimed to provide recommendations for the diagnostic process, screening tools and questionnaires, quantitative sensory testing (QST), microneurography, pain‐related reflexes and evoked potentials, functional neuroimaging and skin biopsy.

TL;DR: It is shown that in complex regional pain syndromes with SMP, physiological activation of cutaneous vasoconstrictor neurons projecting to the painful arm or leg enhances spontaneous pain and hyperalgesia, and postulate that there is a pathological interaction between sympathetic and afferent neurons within the skin.

TL;DR: Parkinsonian tremor is most likely due to oscillating neuronal activity within the CNS, but the neuronal mechanisms underlying these oscillations are not yet clear and three hypotheses would be compatible with the presently available data from animal models and data recorded in patients.