R
R. Pinto
Researcher at University of Porto
Publications - 28
Citations - 1325
R. Pinto is an academic researcher from University of Porto. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 21 publications receiving 1126 citations.
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Journal ArticleDOI
Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.
Mayla Gabriela Silva Borba,Fernando Fonseca Almeida Val,Vanderson de Souza Sampaio,Márcia A. A. Alexandre,Gisely Cardoso de Melo,Marcelo A M Brito,Maria Paula Gomes Mourão,Jose Diego Brito-Sousa,Djane Clarys Baia-da-Silva,Marcus Vinitius de Farias Guerra,Ludhmila Abrahão Hajjar,R. Pinto,Antônio Alcirley da Silva Balieiro,Antonio G. Pacheco,James D. Santos,Felipe Gomes Naveca,Mariana Simão Xavier,André M. Siqueira,Alexandre Vargas Schwarzbold,Julio Croda,Julio Croda,Maurício Lacerda Nogueira,Gustavo Adolfo Sierra Romero,Quique Bassat,Cor Jesus Fernandes Fontes,Bernardino Cláudio de Albuquerque,Cláudio Tadeu Daniel-Ribeiro,Wuelton Marcelo Monteiro,Marcus Lacerda +28 more
TL;DR: The preliminary findings of this study suggest that the higher CQ dosage should not be recommended for critically ill patients with COVID-19 because of its potential safety hazards, especially when taken concurrently with azithromycin and oseltamivir.
Posted ContentDOI
Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study)
Mayla Gabriela Silva Borba,Fernando Fonseca Almeida Val,Vanderson de Souza Sampaio,Márcia A. A. Alexandre,Gisely Cardoso de Melo,Marcelo A M Brito,Maria Paula Gomes Mourão,Jose Diego Brito-Sousa,Djane Clarys Baia-da-Silva,Marcus Vinitius de Farias Guerra,Ludhmila Abrahão Hajjar,R. Pinto,Antônio Alcirley da Silva Balieiro,Felipe Gomes Naveca,Mariana Simão Xavier,Alexandre Salomão,André M. Siqueira,Alexandre Vargas Schwarzbold,Julio Croda,Maurício Lacerda Nogueira,Gustavo Adolfo Sierra Romero,Quique Bassat,Cor Jesus Fernandes Fontes,Bernardino Cláudio de Albuquerque,Cláudio Tadeu Daniel-Ribeiro,Wuelton Marcelo Monteiro,Marcus Lacerda,CloroCovid Team,Fundação de Vigilância em Saúde do Amazonas. Manaus, Am, Brasil.,Mozambique Centro de Investigação em Saúde de Manhiça. Maputo,Spain Icrea. Barcelona +30 more
TL;DR: Preliminary findings suggest that the higher CQ dosage (10-day regimen) should not be recommended for COVID-19 treatment because of its potential safety hazards.
Basic nutritional investigation Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats
E. Teixeira de Lemos,F. Reis,Sofia Baptista,R. Pinto,Bruno Sepodes,Helena Vala,Petronila Rocha-Pereira,G. Correia da Silva,Nolan Ribeiro Bezerra Teixeira,A. Santos Silva,Luzineide Fernandes de Carvalho,F. Teixeira +11 more
TL;DR: In this paper, the effect of exercise on the plasma levels of proinflammatory cytokines, interleukin-6 (IL-6) and tumor necrosis factor- (TNF-), and the anti-inflammatory molecule uric acid in the Zucker diabetic fatty (ZDF) rats that are more prone to develop type 2 diabetes mellitus was evaluated.
Journal ArticleDOI
Mortality Predictors in Patients with Severe Dengue in the State of Amazonas, Brazil.
R. Pinto,Daniel Barros de Castro,Bernardino Cláudio de Albuquerque,Vanderson de Souza Sampaio,Ricardo Augusto dos Passos,Cristiano Fernandes da Costa,Megumi Sadahiro,José Ueleres Braga,José Ueleres Braga +8 more
TL;DR: The study results showed that the best predictor of death from severe dengue is based on the characteristic of age >55 years, together with the clinical signs of gastrointestinal bleeding, hematuria, and low platelet count.
Journal ArticleDOI
Deforestation, drainage network, indigenous status, and geographical differences of malaria in the State of Amazonas.
Wagner Cosme Morhy Terrazas,Vanderson de Souza Sampaio,Daniel Barros de Castro,R. Pinto,Bernardino Cláudio de Albuquerque,Megumi Sadahiro,Ricardo Augusto dos Passos,José Ueleres Braga,José Ueleres Braga +8 more
TL;DR: The results indicated a negative correlation between the two socio-economic indicators (municipal human development index (MHDI) and poverty rate) and the incidence of malaria in the period, which underscores the importance of implementing economic and social development policies articulated with strategic actions of environmental protection and health care for the population.