Rafal M. Pielak

TL;DR: A flexible microfluidic device that adheres to human skin that collects and analyzes sweat during exercise and could be used during athletic or military training and adapted to test other bodily fluids such as tears or saliva is developed.

TL;DR: Structural and functional experiments on the mechanism of drug inhibition and resistance of the S31N drug-resistant mutant of M2, a mutant of the highly pathogenic avian influenza subtype H5N1, show that replacing Ser-31 with Asn has little effect on the structure of the channel pore, but dramatically reduces drug binding to the allosteric site.

TL;DR: This work introduces an ultrathin, soft, skin-conforming sensor technology that offers advanced capabilities in continuous and precise blood flow mapping and establishes a set of experimental procedures and theoretical models for quantitative measurements and guidelines in design and operation.

TL;DR: This review summarizes the current understanding of how protons are conducted through the M2 channel from a structural point of view, as well as the modes by which important channel gating elements function during proton conduction.

TL;DR: Single molecule measurements of the pM HC:TCR:ZAP70 complex indicate that TCR triggering is stoichiometric with agonist pMHC in a 1:1 ratio, which means any signal amplification must occur downstream of T CR triggering.