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Raffaele Bruno

Researcher at University of Pavia

Publications -  322
Citations -  14690

Raffaele Bruno is an academic researcher from University of Pavia. The author has contributed to research in topics: Medicine & Hepatitis C. The author has an hindex of 52, co-authored 275 publications receiving 11262 citations. Previous affiliations of Raffaele Bruno include University of Modena and Reggio Emilia.

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Viral dynamics and pharmacokinetics of peginterferon alpha-2a and peginterferon alpha-2b in naive patients with chronic hepatitis c: a randomized, controlled study.

TL;DR: Once-weekly administration of peginterferon alpha-2b (1.0 microg/kg/wk) may be insufficient for continuous interferon exposure; twice- weekly administration may help avoid increases in viral replication as interferons levels decline.
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Low frequency of severe hepatotoxicity and association with HCV coinfection in HIV-positive patients treated with HAART.

TL;DR: Hepatitis C coinfection and elevated ALT levels at HAART initiation are important predictors of progression to alanine aminotransferase levels > or =200 IU/L; stavudine-containing regimens were associated with a lower risk compared with zidovudineThe Lancet records suggest that highly active antiretroviral therapy is strongly effective in reducing morbidity and mortality in HIV-1-positive individuals.
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Radiographic findings in 240 patients with COVID-19 pneumonia: time-dependence after the onset of symptoms.

TL;DR: The predominant lung changes were GGO and reticular alteration, while consolidation was less frequent, and the typical distribution pattern was bilateral, peripheral, or both peripheral and central and involved predominantly the lower and middle fields.