R
Rajinder Parshad
Researcher at All India Institute of Medical Sciences
Publications - 123
Citations - 2349
Rajinder Parshad is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 26, co-authored 113 publications receiving 2084 citations. Previous affiliations of Rajinder Parshad include Council of Scientific and Industrial Research.
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Journal ArticleDOI
Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a prospective randomized trial
Surendra B. Kolla,Sandeep Aggarwal,Ajay Kumar,R. Kumar,Sunil Chumber,Rajinder Parshad,Vuthaluru Seenu +6 more
TL;DR: Early laparoscopic cholecystectomy for acute choleCystitis is safe and feasible, offering the additional benefit of a shorter hospital stay, and should be offered to patients with acute choelcystitis.
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Expression of DNA methyltransferases in breast cancer patients and to analyze the effect of natural compounds on DNA methyltransferases and associated proteins.
Sameer Mirza,Gayatri Sharma,Rajinder Parshad,Sidhartha Datta Gupta,Pranav Pandya,Ranju Ralhan +5 more
TL;DR: The results demonstrate that the natural compounds, EGCG, genistein, withaferin A, curcumin, resveratrol, and guggulsterone, have the potential to reverse the epigenetic changes.
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Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast
Chandra Prakash Prasad,Chandra Prakash Prasad,Gayatri Rath,Sandeep Mathur,Dinesh Bhatnagar,Rajinder Parshad,Ranju Ralhan +6 more
TL;DR: Clinical evidence is provided in support of Wnt/β-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3β with β- catenin in implementing EMT in these cells.
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Promoter hypermethylation of TMS1, BRCA1, ERα and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients
Sameer Mirza,Gayatri Sharma,Chandra Prakash Prasad,Rajinder Parshad,Anurag Srivastava,Siddartha Dutta Gupta,Ranju Ralhan +6 more
TL;DR: Investigation of invasive ductal carcinoma of breast and paired serum DNA determined methylation status of tumor suppressor genes TMS1, BRCA1, ERalpha and PRB confirmed the hypothesis that promoter methylation is an important mechanism for transcriptional silencing of these genes in breast cancer in this population and underscores the potential utility of DNA methylation based screening of serum.
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Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients
Gayatri Sharma,Sameer Mirza,Rajinder Parshad,Anurag Srivastava,Siddartha Datta Gupta,Pranav Pandya,Ranju Ralhan +6 more
TL;DR: The potential utility of DNA methylation of these genes in serum as a promising biomarker and can serve as a surrogate for tumorDNA methylation for diagnosis and prognosis of breast cancer are underscored.