Ralf Stanewsky

TL;DR: Cryb flies are rhythmic in constant darkness, correlating with robust PER and TIM cycling in certain pacemaker neurons, and is an apparent null mutation in a gene encoding Drosophila's version of the blue light receptor cryptochrome.

TL;DR: CRY overexpression in brain pacemaker cells increases behavioral photosensitivity, and this restricted CRY expression also rescues all circadian defects of cry(b) behavior.

TL;DR: Noninvasive, high time-resolution experiments allowing high-throughput monitoring of circadian bioluminescence rhythms in individual living adults for several days solve several problems and provides a general strategy for the analysis of rhythmic time series in the study of molecular rhythms.

TL;DR: It is shown that Drosophila uses at least three light input pathways for this entrainment: cryptochrome, acting in the pacemaker cells themselves, the compound eyes, and extraocular photoreception, possibly involving an internal structure known as the Hofbauer-Buchner eyelet, which is located underneath the compound eye and projects to thepacemaker center in the brain.

TL;DR: It is shown here that Pdf01 mutants are not able to adapt their activity to long photoperiods in a wild-type manner, indicating that PDF is crucial for adjusting cycling amplitude, period, and phase of the different players in the circadian clock.