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Ralf Stumm

Researcher at University of Jena

Publications -  63
Citations -  4296

Ralf Stumm is an academic researcher from University of Jena. The author has contributed to research in topics: Chemokine receptor & Receptor. The author has an hindex of 33, co-authored 57 publications receiving 3764 citations. Previous affiliations of Ralf Stumm include Otto-von-Guericke University Magdeburg & Schiller International University.

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Journal ArticleDOI

CXCR4 Regulates Interneuron Migration in the Developing Neocortex

Ralf Stumm, +7 more
- 15 Jun 2003 - 
TL;DR: These findings suggest that SDF-1, which is highly expressed in the embryonic leptomeninx, selectively regulates migration and layer-specific integration of CXCR4-expressing interneurons during neocortical development.
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A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia

Ralf Stumm, +7 more
- 15 Jul 2002 - 
TL;DR: The cellular expression of SDF-1 isoforms and CXCR4 in the brain of mice receiving systemic lipopolysaccharide (LPS) or permanent focal cerebral ischemia is examined to find the isoform-specific regulation of S DF-1 expression modulates neurotransmission and cerebral infiltration via distinct CX CR4-dependent pathways.
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Cxcr7 controls neuronal migration by regulating chemokine responsiveness.

Juan Antonio Sánchez-Alcañiz, +10 more
- 13 Jan 2011 - 
TL;DR: Cxcr7 is necessary to regulate Cxcr4 protein levels, thereby adapting chemokine responsiveness in migrating cells, and this demonstrates that aChemokine receptor modulates the function of another chemokin receptor by controlling the amount of protein that is made available for signaling at the cell surface.
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Morphine induces terminal μ‐opioid receptor desensitization by sustained phosphorylation of serine‐375

Stefan Schulz, +5 more
- 18 Aug 2004 - 
TL;DR: It is shown that morphine promotes terminal MOR desensitization by inducing a persistent modification of Ser375, which is a selective phosphorylation of the carboxy‐terminal residue 375.
Journal ArticleDOI

Differential β-Arrestin Trafficking and Endosomal Sorting of Somatostatin Receptor Subtypes

Giovanni Tulipano, +5 more
- 14 May 2004 - 
TL;DR: It is shown that somatostatin receptors profoundly differ in patterns of β-arrestin mobilization and endosomal sorting, which may provide important clues about the regulation of receptor responsiveness during long-term administration of som atostatin analogs.