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Rami Musharrafieh

Researcher at University of Arizona

Publications -  29
Citations -  884

Rami Musharrafieh is an academic researcher from University of Arizona. The author has contributed to research in topics: Virus & Antibody. The author has an hindex of 14, co-authored 23 publications receiving 541 citations. Previous affiliations of Rami Musharrafieh include University of New Mexico & Scripps Research Institute.

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Journal ArticleDOI

Nasal immunity is an ancient arm of the mucosal immune system of vertebrates

Luca Tacchi, +7 more
- 22 Oct 2014 - 
TL;DR: It is found that NALT is present in rainbow trout and that it resembles other teleost mucosa-associated lymphoid tissues, and is capable of mounting strong anti-viral immune responses following nasal delivery of a live attenuated viral vaccine.
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Effects of transportation stress and addition of salt to transport water on the skin mucosal homeostasis of rainbow trout (Oncorhynchus mykiss)

Luca Tacchi, +5 more
- 01 Jan 2015 - 
TL;DR: The data clearly indicate the skin and skin microbiota of rainbow trout undergo important physiological responses during stress, and a new mechanism by which salt is an effective stress mitigator in some fish species.
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Discovery of cyclosporine A and its analogs as broad-spectrum anti-influenza drugs with a high in vitro genetic barrier of drug resistance.

Chunlong Ma, +3 more
- 01 Sep 2016 - 
TL;DR: It is discovered that CsA and its analogs have broad-spectrum antiviral activity against multiple influenza A and B strains, including strains that are resistant to either NA or M2 inhibitors or both.
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An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses

Yanmei Hu, +6 more
- 01 Apr 2017 - 
TL;DR: This study represents the first report demonstrating the in vivo antiviral efficacy of inhibitors targeting M2 mutants, and suggests that inhibitors targeting drug‐resistant M 2 mutants are promising antiviral drug candidates worthy of further development.
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Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV-D68)

Rami Musharrafieh, +7 more
- 03 Apr 2019 - 
TL;DR: Three compounds 10a, 12a, and 12c were identified to have significantly improved potency and a high selectivity index compared with dibucaine against five different strains of EV-D68 viruses, suggesting they might be further developed for the treatment of both respiratory infection as well as neuronal infection.