R
Ramzi Shawahna
Researcher at An-Najah National University
Publications - 90
Citations - 1690
Ramzi Shawahna is an academic researcher from An-Najah National University. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 20, co-authored 76 publications receiving 1245 citations. Previous affiliations of Ramzi Shawahna include Paris Descartes University & Islamia University.
Papers
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Journal ArticleDOI
Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
Ramzi Shawahna,Yasuo Uchida,Xavier Declèves,Sumio Ohtsuki,Salah Yousif,Sandrine Dauchy,Aude Jacob,Francine Chassoux,Catherine Daumas-Duport,Pierre-Olivier Couraud,Tetsuya Terasaki,Jean Michel Scherrmann +11 more
TL;DR: The extensive investigation of gene and protein patterns of transporters and metabolizing enzymes provides new molecular information for understanding drug entry and metabolism in the human blood-brain barrier.
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Interplay of Drug Metabolizing CYP450 Enzymes and ABC Transporters in the Blood-Brain Barrier
TL;DR: Recent studies on the expression, regulation and function of CYP450 and ABC transporters in the rodent and human BBBs are covered, which makes it a determining element of brain drug concentrations and thus of the effects of centrally acting drugs.
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Herbal remedies use by breast cancer patients in the West Bank of Palestine.
TL;DR: The use of herbal remedies was associated with educational level, time since diagnosis, type of surgery use, and use of endocrine therapy, and it was apparent that the majority of users were satisfied with herbal remedies use.
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Electronic prescribing reduces prescribing error in public hospitals
Ramzi Shawahna,Nisar-Ur Rahman,Mahmood Ahmad,Marcel Debray,Marjo Yliperttula,Xavier Declèves +5 more
TL;DR: The study evaluated the impact of introducing electronic inpatient records and electronic prescribing in the reduction of prescribing errors in a public hospital in Pakistan.
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Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes
TL;DR: This text reviews the available animal and in vitro BBB models with special emphasis on the situation in freshly isolated human brain microvessels and the unique tightness between brain endothelial cells, drug transport pathways and metabolic capacity.