M
Marjo Yliperttula
Researcher at University of Helsinki
Publications - 162
Citations - 7369
Marjo Yliperttula is an academic researcher from University of Helsinki. The author has contributed to research in topics: Drug delivery & Self-healing hydrogels. The author has an hindex of 44, co-authored 154 publications receiving 6040 citations. Previous affiliations of Marjo Yliperttula include University of Padua & Orion Corporation.
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Journal ArticleDOI
Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells.
Heikki Saari,Elisa Lázaro-Ibáñez,Tapani Viitala,Elina Vuorimaa-Laukkanen,Pia Siljander,Marjo Yliperttula +5 more
TL;DR: Cancer cell-derived EVs can be used as effective carriers of Paclitaxel to their parental cells, bringing the drug into the cells through an endocytic pathway and increasing its cytotoxicity.
Journal ArticleDOI
Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
Stefano Fais,Lorraine O'Driscoll,Francesc E. Borràs,Edit I. Buzás,Giovanni Camussi,Francesco Cappello,Joana Carvalho,Anabela Cordeiro da Silva,Hernando A. del Portillo,Samir El Andaloussi,Samir El Andaloussi,Tanja Ficko Trček,Roberto Furlan,An Hendrix,Ihsan Gursel,Veronika Kralj-Iglič,Bertrand Kaeffer,Maja Kosanović,Marilena E. Lekka,Georg Lipps,Mariantonia Logozzi,Antonio Marcilla,Marei Sammar,Alicia Llorente,Irina Nazarenko,Carla Oliveira,Gabriella Pocsfalvi,Lawrence Rajendran,Graça Raposo,Eva Rohde,Pia Siljander,Guillaume van Niel,M. Helena Vasconcelos,María Yáñez-Mó,Marjo Yliperttula,Natasa Zarovni,Apolonija Bedina Zavec,Bernd Giebel +37 more
TL;DR: The high potential of nanosized EVs for both diagnostic and therapeutic areas of nanomedicine, as demonstrated by the European Network on Microvesicles and Exosomes in Health and Disease (ME-HAD), is demonstrated.
Journal ArticleDOI
Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture
Madhushree Bhattacharya,Melina Malinen,Patrick Laurén,Yan-Rou Lou,Saara W. Kuisma,Liisa Kanninen,Martina Lille,Anne Corlu,Christiane Guguen-Guillouzo,Olli Ikkala,Antti Laukkanen,Arto Urtti,Marjo Yliperttula +12 more
TL;DR: It is demonstrated that native nanofibrillar cellulose (NFC) hydrogels derived from the abundant plant sources provide the desired functionalities and generates a feasible and sustained microenvironment for 3D cell culture for potential applications, such as drug and chemical testing, tissue engineering, and cell therapy.
Journal ArticleDOI
Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2.
TL;DR: The current functional knowledge on LAT1 and LAT2 is presented with emphasis on their potential involvement in pharmacokinetics, and cross-linked heterodimers of light chain with different heavy chains are presented.
Journal ArticleDOI
Gold nanoparticles enable selective light-induced contents release from liposomes.
Lauri Paasonen,Timo Laaksonen,Christoffer Johans,Marjo Yliperttula,Kyösti Kontturi,Arto Urtti +5 more
TL;DR: A novel proof of principle demonstration for contents release from liposomes that can be selectively activated by light irradiation is presented, and triggered contents release was triggered by UV light-induced heating of the gold nanoparticles.