Showing papers in "Journal of Ethnopharmacology in 2016"

TL;DR: The botany, ethnopharmacology, phytochemistry, pharmacology and toxicology of P. notoginseng is summarized comprehensively for the first time and the plant has pharmacological effects on the cardiovascular system, immune system as well as anti-inflammatory, anti-atherosclerotic, haemostatic and anti-tumour activities.

TL;DR: The data reviewed here revealed that M. officinalis is a potential source for the treatment of a wide range of diseases especially anxiety and some other CNS disorders, though confirmatory trials are warranted to substantiate these effects in the clinical setting.

TL;DR: Extensive basic and clinical studies on N. sativa seed powder, oil, extracts, and thymoquinone showed valuable therapeutic effects on different disorders with a wide range of safe doses, however, there were some confounding factors in the reviewed clinical trials.

TL;DR: This study reviews the progress in chemical analysis of A. sinensis and its preparations and discusses the reasonable selection of marker compounds based on high concentrations, analytical methods, and commercial availabilities with the goal of developing quick, accurate, and applicable analytical approaches for quality evaluation and establishing harmonised criteria for the analysis.

TL;DR: Clinical practice and animal experiments indicate that TCM formulas provide a definite therapeutic effect on osteoporosis, and the proposed antiosteoporotic mechanism involves multi regulatory pathways, such as Wnt/β-catenin, BMP/Smad, MAPK pathway and RANKL/OPG system.

TL;DR: There is still, however, the need for definitive research and clarification of other bioactive compounds using bioactivity-guided isolation strategies, and the possible mechanism of action as well as potential synergistic or antagonistic effects of multi-component mixtures derived from Gastrodia elata Blume need to be evaluated.

TL;DR: An overview of the phytochemistry, ethnomedicinal use, pharmacological activities and safety of plant materials from Aquilaria spp.

TL;DR: The proven E. camaldulensis essential oil synergistic interactions with conventional antibiotics could lead to the development of new treatment strategies of infections caused by MDR A. baumannii strains in the term of antibiotic dose reduction.

TL;DR: A first complete review of traditional uses of wild food plants used as vegetables and their preparations, indicating their phytochemical and nutritional profile, and discussing topics such as the taste of plants used in the recipes.

TL;DR: Results from preclinical and clinical studies on herb-microbiota interactions showed that traditional herbs could exert heath promotion and disease prevention roles via influencing the gut microbiota structure and novel mechanistic understanding of the traditional herbs that exhibit poor oral bioavailability.

TL;DR: This review summarizes the achievements of the investigations in botany, phytochemistry, quality control, traditional uses, pharmacological activities and clinical studies on O. japonicus and describes the shortcomings of studies on this herbal drug, which serves as the basis of further scientific research and development of this traditional herbal drug.

TL;DR: It has been found that RAP itself did not have any cytotoxic effect on mouse mammary carcinoma 4T1 cells, but it significantly enhanced cytotoxicity of the supernatant of RAW264.7 cells, suggesting that TLR4 is a receptor of RAP and mediates its immunomodulating activity.

TL;DR: Fruits of Cornus mas L. (cornelian cherry) are a potential source for treatment of diabetes, obesity, hyperlipidemia and gastrointestinal disorders and are non-toxic and safe food on acute toxicity studies in rat and human models.

TL;DR: The traditional use of medicinal plants for the treatment of human and livestock ailments is important to indigenous communities in the northern parts of Pakistan, a... as discussed by the authors, and the authors of this article

TL;DR: Although, a variety of medicinal plants for wound healing can be found in literature, there is a need for the isolation and characterization of the bioactive compounds responsible for the wound healing properties.

TL;DR: The present study has highlighted the rich herbal knowledge about newfound medicinal plants and their new uses in the Mediterranean region, which could be useful not only in facilitating other studies such as phytochemical and pharmacological investigations and upgrading the sources of biomolecules beneficial to people but also in reopening discussion on pharmacovigilance in herbal medicine as an imperative requirement for local authorities.

TL;DR: There is variation in the availability and quality of pharmacological, chemical and clinical studies to explain traditional use of medicinal plants used to manage diabetes in Central America and of the current scientific knowledge that might explain their traditional use.

TL;DR: It is indicated that it is important always to include bacterial and mammalian tests, with at least one in vivo assay, in order to conduct a thorough study concerning the possible genotoxic effects of a medicinal plant.

TL;DR: This review highlights the botany, ethnopharmacology, phytochemistry, biological activities, and toxicology of S. japonica based on studies published in the last six decades and offers promising data for further studies as well as the commercial exploitation of this traditional medicine.

TL;DR: GP could improve the memory ability and reduce the content of Aβ1-42 and p-tau in AD rats and the anti-AD effects of GP were in part mediated by PI3K/Akt signaling pathway activation.

TL;DR: These findings suggest that topical application of FOE or its active ingredients exhibit significantly anti-inflammatory and analgesic effects through inhibiting nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression.

TL;DR: Acer species can be used to treat rheumatism, hepatic disorders, eye disease, pain, etc. effectively and reports on the toxicity of Acer species to humans are very limited, and the major safety concern of these plants is in the veterinary field.

TL;DR: Corilagin, repandusinic acid A, and mallotinin were potent α-glucosidase inhibitors contributing significantly to the inhibitory effect observed for the water extracts of P. amarus and P. urinaria.

TL;DR: Current ethnomedicinal practices of Hutsuls living on both sides of the border are more extensive than those reported in historical sources, and Divergences in current medicinal plant use are much greater than in the use of wild food plants.

TL;DR: Local medicinal plant knowledge is rich in the High Atlas, where local populations still rely on medicinal plants for healthcare, and experimental evidence of safe and effective use of medicinal plants is found, but the use of eight poisonous species is highlighted.

TL;DR: The results suggest that Liuwei Dihuang decoction could intervene insulin resistance of T2DM, in part, through regulation of canonical PI3K/Akt signaling pathway of T1DM rats in liver.

TL;DR: This study demonstrates the promising anti-QS and antibiofilm activities of PBE and its active metabolite phytol, and confirms the ethnopharmacological applications of these leaves against S. marcescens infections.

TL;DR: It is revealed the importance to document and launch list of all possible plants that are used in ethno medicinal practices in the study area to ratify the efficacy and safety of the medicinal plants species.

TL;DR: The role of PF markedly suppressed high glucose induced Schwann cells oxidative stress by decreasing ROS and MDA levels and increasing GST and GPX activity and activation of Nrf2/ARE pathway and Bcl-2-related apoptotic pathway is found.

TL;DR: These findings demonstrate the antioxidant and neuroprotective activities of the D. indusiata polysaccharide DiPS in wild-type and neurodegenerative Caenorhabditis elegans models and provide an important pharmacological basis for the therapeutic potential of D. indisiata in Neurodegeneration.