R
Randall K. Saiki
Researcher at Hoffmann-La Roche
Publications - 20
Citations - 6876
Randall K. Saiki is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Nucleic acid & Nucleic acid sequence. The author has an hindex of 12, co-authored 20 publications receiving 6872 citations. Previous affiliations of Randall K. Saiki include Cetus Corporation.
Papers
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Patent
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
Kary Banks Mullis,Norman Arnheim,Randall K. Saiki,Henry A. Erlich,Glenn Thomas Horn,Stephen J. Scharf +5 more
TL;DR: In this paper, the authors proposed a method for synthesizing nucleic acid sequences using primers, which can be repeated stepwise or simultaneously and can be replicated as often as desired.
Patent
Homogeneous assay system
TL;DR: In this paper, a process of detecting a target nucleic acid using labeled oligonucleotides using the 5′ to 3′ nuclease activity of a NAC polymerase was described.
Patent
Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids and kits therefor
TL;DR: In this paper, single or multiple nucleotide variations in nucleic acid sequence can be detected by a process whereby the sample suspected of containing the relevant nucleic acids is repeatedly treated with primers, nucleotide triphosphates, and an agent for polymerization of the triphophosphates and then denatured, in a process which amplifies the sequence containing the nucleotide variation.
Patent
Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
TL;DR: In this paper, a single or multiple nucleotide variations in nucleic acid sequence can be detected by a process whereby the sample suspected of containing the relevant nucleic acids is repeatedly treated with primers, nucleotide triphosphates, and an agent for polymerization of the triosphates and then denatured, in a process which amplifies the sequence containing the nucleotide variation if it is present.
Journal ArticleDOI
HLA-DR, DQ and DP typing using PCR amplification and immobilized probes.
Henry A. Erlich,Teodorica L. Bugawan,Ann B Begovich,Stephen J. Scharf,Robert L. Griffith,Randall K. Saiki,Russell Higuchi,P.S. Walsh +7 more
TL;DR: A method of analysing class II sequence polymorphism based on polymerase chain reaction (PCR) amplification and hybridization with oligonucleotide probes with the aim of identifying new alleles at the DRB1, DPB1 and DQB1 loci.