Raquel P. Deering

TL;DR: Patients with melanoma in whom fatal myocarditis developed after treatment with ipilimumab and nivolumab were having a rare, potentially fatal, T-cell-driven drug reaction, according to Pharmacovigilance studies.

TL;DR: In this article , the authors evaluated the clinical activity of neoadjuvant cemiplimab (an anti-PD-1) in patients with resectable hepatocellular carcinoma.

TL;DR: In this paper , exome sequence data from 628,388 individuals was used to identify 24 risk loci in 40,208 carriers of clonal haematopoiesis of indeterminate potential and link them to other conditions including COVID-19, cardiovascular disease and cancer.

TL;DR: Using genome-wide and exome-wide association analyses, 27 loci are identified where germline genetic variation influences CH/CHIP predisposition, including missense variants in the DNA-repair gene PARP1 and the lymphocytic antigen coding gene LY75 that are associated with reduced incidence of CH/ CHIP.

TL;DR: Odronextamab is a CD20 × CD3 bispecific antibody that has demonstrated durable responses and a manageable safety profile in patients with R/R B‐NHL in a first‐in‐human trial (NCT02290951).