R
Raul D. Santos
Researcher at University of São Paulo
Publications - 463
Citations - 21660
Raul D. Santos is an academic researcher from University of São Paulo. The author has contributed to research in topics: Familial hypercholesterolemia & Medicine. The author has an hindex of 56, co-authored 404 publications receiving 16997 citations. Previous affiliations of Raul D. Santos include Albert Einstein Hospital.
Papers
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Journal ArticleDOI
Beyond Statins and PCSK9 Inhibitors: Updates in Management of Familial and Refractory Hypercholesterolemias.
Fabiana Rached,Raul D. Santos +1 more
TL;DR: Inclisiran is a small interfering ribonucleic acid inhibitor that reduces the hepatic production of PCSK9 that induces robust LDL-C lowering, similar to monoclonal antibodies, with the advantage of 2 or 3 injections per year.
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Coronary artery calcification progression and cardiovascular events in renal transplant recipients, bad inheritance from previous kidney disease: commentary on the study of Roe et al.
TL;DR: The authors found that not only CAC presence at baseline but its progression was associated with cardiovascular events after mean 18-month follow-up, and those presenting CAC at baseline came from a worse metabolic and inflammatory envionment and inherited a more severe vascular disease.
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Health related quality of life in individuals at high risk for familial hypercholesterolemia undergoing genetic cascade screening in Brazil
Ana Cristina Fagundes Souto,Marcio H. Miname,Julia Tizue Fukushima,Cinthia E. Jannes,José Eduardo Krieger,Martin S. Hagger,Alexandre C. Pereira,Raul D. Santos +7 more
TL;DR: HRQoL is not reduced in both index cases and first-degree relatives of individuals at high risk of FH undergoing genetic cascade screening in comparison with their non-affected counterparts.
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A synergistic relationship of elevated low-density lipoprotein cholesterol levels and systolic blood pressure with coronary artery calcification.
Kiran Musunuru,Khurram Nasir,Shivda Pandey,Catherine C. Campbell,Jose A.M. Carvalho,Romeu Meneghello,Matthew J. Budoff,Roger S. Blumenthal,Raul D. Santos,Raul D. Santos +9 more
TL;DR: The finding of an interaction between SBP and LDL-C relation to CAC in asymptomatic men support the response-to-injury model of atherogenesis.
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The time is now: Achieving FH paediatric screening across Europe – The Prague Declaration
Nicole Bedlington,Marianne Abifadel,Birgit Beger,Mafalda Bourbon,Héctor Bueno,Richard Ceska,Kristyna Cillíková,Zdenka Cimická,Magdalena Daccord,Carine de Beaufort,Kanika I. Dharmayat,Brian A. Ference,Tomáš Freiberger,Marius Geanta,Samuel S. Gidding,Urh Groselj,Martin Halle,Neil Johnson,Tanja Novakovic,Ondřej Májek,Athanasios Pallidis,Noël Peretti,Fausto J. Pinto,Kausik Kosh Ray,Bleddyn Rees,J. Reeve,Zeljko Reiner,Raul D. Santos,Heribert Schunkert,J. Sikonja,Milka Sokolović,Lâle Tokgözoğlu,Michal Vrablík,Albert Wiegman,Iñaki Gutiérrez-Ibarluzea +34 more
TL;DR: The Prague meeting addressed the outstanding barriers to the systematic implementation of FH paediatric screening across Europe and presented the key points from the Prague meeting and concrete actions needed to move forward.