R
Raul D. Santos
Researcher at University of São Paulo
Publications - 463
Citations - 21660
Raul D. Santos is an academic researcher from University of São Paulo. The author has contributed to research in topics: Familial hypercholesterolemia & Medicine. The author has an hindex of 56, co-authored 404 publications receiving 16997 citations. Previous affiliations of Raul D. Santos include Albert Einstein Hospital.
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Journal ArticleDOI
Familial hypercholesterolemia in Brazil: Cascade screening program, clinical and genetic aspects
Cinthia E. Jannes,Raul D. Santos,Pamela R.S. Silva,Luciana Turolla,Ana Carolina Moron Gagliardi,Julia Daher Carneiro Marsiglia,Ana Paula Marte Chacra,Marcio H. Miname,Viviane Z. Rocha,Wilson Salgado Filho,José Eduardo Krieger,Alexandre C. Pereira +11 more
TL;DR: Genetic familial hypercholesterolemia cascade screening is feasible in Brazil and leads to identification of a mutation in approximately half of the index cases with higher rates of success in their relatives.
Journal ArticleDOI
Achievement of low-density lipoprotein cholesterol goals in 18 countries outside Western Europe: The International ChoLesterol management Practice Study (ICLPS).
Nicolas Danchin,Wael Almahmeed,Khalid Al-Rasadi,Joseph Azuri,Abdelkrim Berrah,Carlos Alberto Cuneo,Yuri Karpov,Upendra Kaul,Meral Kayıkçıoğlu,Olena Mitchenko,Álvaro J. Ruiz,Carlos A Aguilar Salinas,Raul D. Santos,Florence Mercier,Dirk J. Blom +14 more
TL;DR: These observational data suggest that the achievement of LDL-C goals is suboptimal in selected countries outside Western Europe and efforts are needed to improve the management of patients using combination therapy and/or more intensive LLTs.
Journal ArticleDOI
Phosphorus Is Associated with Coronary Artery Disease in Patients with Preserved Renal Function
Ana L.E. Cancela,Raul D. Santos,Silvia M. Titan,Patricia Taschner Goldenstein,Carlos E. Rochitte,Pedro A. Lemos,Luciene M. Reis,F. G. Graciolli,Vanda Jorgetti,Rosa M.A. Moysés +9 more
TL;DR: In this article, the relation of phosphorus and coronary calcification and atherosclerosis in the setting of normal renal function was evaluated in patients with suspected coronary artery disease and undergoing elective coronary angiography, with a creatinine clearance > 60 ml/min/1.73 m(2).
Journal ArticleDOI
ClinVar database of global familial hypercholesterolemia-associated DNA variants
Michael A. Iacocca,Joana Rita Chora,Joana Rita Chora,Alain Carrié,Tomáš Freiberger,Sarah Leigh,Joep C. Defesche,C. Lisa Kurtz,Marina T. DiStefano,Raul D. Santos,Steve E. Humphries,Pedro Mata,Cinthia E. Jannes,Amanda J. Hooper,Katherine Wilemon,Pascale Benlian,Robert O'Connor,John Garcia,Hannah Wand,Lukas Tichy,Eric J.G. Sijbrands,Robert A. Hegele,Mafalda Bourbon,Mafalda Bourbon,Joshua W. Knowles +24 more
TL;DR: To further reform interpretation of FH‐associated variants, areas for improvement in variant submissions were identified; these include a need for more detailed submissions and submission of supporting variant‐level data, both retrospectively and prospectively.
Journal ArticleDOI
Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA
Ruud S. Kootte,Loek P. Smits,Fleur M. van der Valk,Jean-Louis Dasseux,Constance Keyserling,Ronald Barbaras,John F. Paolini,Raul D. Santos,Theo H. van Dijk,Geesje M. Dallinga-van Thie,Aart J. Nederveen,Willem J. M. Mulder,G. Kees Hovingh,John J.P. Kastelein,Albert K. Groen,Erik S.G. Stroes +15 more
TL;DR: In FHA-subjects, CER-001 stimulates cholesterol mobilization and reduces artery wall dimension and inflammation, supporting further evaluation of C ER-001 in FHA patients.