Raul D. Santos

TL;DR: In this article, the authors provide clinical guidance and an overview of the available data on the use of SGLT2 inhibitors in patients with heart failure with reduced ejection fraction.

TL;DR: In this article, the authors compare cardiovascular risk categorization and statin eligibility based on the Brazilian guideline with those based on AHA/ACC guideline in primary prevention patients, and conclude that the Brazilian guidelines classifies a larger proportion of primary preventive patients into higher risk categories and substantially increases the eligibility of statin therapy.

TL;DR: Homozygous familial hypercholesterolemia (HoFH) is a devastating codominant autosomal disease mostly caused by loss off function variants affecting the LDL receptor gene (LDLR) and is characterized by extremely elevated plasma LDL-cholesterol (LDL-C), diffuse cutaneous and tendinous xanthomas, corneal arcus, and early diffuse atherosclerotic cardiovascular disease (ASCVD) as discussed by the authors.

TL;DR: No changes were found in chylomicron metabolism is in the acute phase of myocardial infarction and high-density lipoprotein cholesterol and apolipoprotein AI were lower on the seventh day when compared to the 45th day post acute myocardIAL infarctions.

TL;DR: The findings strongly suggest that fitness is associated with a favorable HR profile and is modified by BMI, and Intervention programs should place emphasis on fitness and not only on weight loss.