R
Ravinder Reddy
Researcher at University of Pennsylvania
Publications - 259
Citations - 12837
Ravinder Reddy is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Magnetic resonance imaging & Cartilage. The author has an hindex of 57, co-authored 249 publications receiving 11091 citations. Previous affiliations of Ravinder Reddy include Osmania Medical College & National Institutes of Health.
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Journal ArticleDOI
Magnetic resonance imaging of glutamate
Kejia Cai,Mohammad Haris,Anup Singh,Feliks Kogan,Joel H. Greenberg,Hari Hariharan,John A. Detre,Ravinder Reddy +7 more
TL;DR: In a rat brain tumor model with blood-brain barrier disruption, intravenous glutamate injection resulted in a clear elevation of GluCEST and a similar increase in the proton magnetic resonance spectroscopy signal of glutamate, demonstrating the feasibility of using GLUCEST for mapping relative changes in glutamate concentration, as well as pH, in vivo.
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Proteoglycan-induced changes in T1ρ-relaxation of articular cartilage at 4T
Sarma V.S. Akella,Ravinder R. Regatte,Alexander J. Gougoutas,Arijitt Borthakur,Erik M. Shapiro,J. Bruce Kneeland,John S. Leigh,Ravinder Reddy +7 more
TL;DR: Proteoglycan depletion‐induced changes in T1ρ (spin‐lattice relaxation in rotating frame) relaxation and dispersion in articular cartilage were studied at 4T and showed a strong correlation between changes in PG and T1RH.
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T1ρ‐relaxation in articular cartilage: Effects of enzymatic degradation
Umamaheswar Duvvuri,Ravinder Reddy,Saurabh D. Patel,Jonathan H. Kaufman,J B Kneeland,John S. Leigh +5 more
TL;DR: The results suggest that T1ρ measurements are selectively sensitive to proteoglycan content, and the potential of this method in distinguishing the early degenerative changes in cartilage associated with osteoarthritis is discussed.
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T1rho relaxation mapping in human osteoarthritis (OA) cartilage: comparison of T1rho with T2.
TL;DR: To quantify the spin‐lattice relaxation time in the rotating frame (T1ρ) in various clinical grades of human osteoarthritis cartilage specimens obtained from total knee replacement surgery, and to correlate the T1ρ with OA disease progression and compare it with the transverse relaxation time (T2).
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23Na MRI Accurately Measures Fixed Charge Density in Articular Cartilage
TL;DR: The feasibility of calculating FCD by 23Na MRI is shown and MRI protocols for human studies, in vivo, are introduced and employed in quantifying the FCD of articular cartilage of human volunteers in vivo.