R
Raymond Meleady
Researcher at Boston Children's Hospital
Publications - 12
Citations - 3722
Raymond Meleady is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Risk factor & Homocysteine. The author has an hindex of 11, co-authored 12 publications receiving 3633 citations.
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Journal ArticleDOI
Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project.
Graham Im,Leslie Daly,Helga Refsum,Killian Robinson,Lars Brattström,Per Magne Ueland,Roberto Palma-Reis,Godfried H.J. Boers,Richard G. Sheahan,Israelsson B,Cuno S.P.M. Uiterwaal,Raymond Meleady,Dorothy McMaster,Petra Verhoef,Jacqueline C.M. Witteman,Paolo Rubba,Bellet H,Jan C. Wautrecht,de Valk Hw,Sales Lúis Ac,Parrot-Rouland Fm,K.S. Tan,I.M. Higgins,Danielle Garcon,Generoso Andria +24 more
TL;DR: An increased plasma total homocysteine level confers an independent risk of vascular disease similar to that of smoking or hyperlipidemia, and compared with nonusers of vitamin supplements, the small number of subjects taking such vitamins appeared to have a substantially lower risk ofascular disease, a proportion of which was attributable to lower plasma homocy steine levels.
Journal ArticleDOI
Plasma Homocysteine as a Risk Factor for Vascular Disease: The European Concerted Action Project
Ian D. Graham,Leslie Daly,Helga Refsum,Killian Robinson,Lars E. Brattstr M,Per Magne Ueland,Roberto Palma-Reis,Godfried H.J. Boers,Richard G. Sheahan,B. Israelsson,Cuno S.P.M. Uiterwaal,Raymond Meleady,Dorothy McMaster,Petra Verhoff,Jacqueline C.M. Witteman,Paolo Rubba,H L Ne Bellet,Jan C. Wautrecht,Harold W. De Valk,Armando C. Sales Luis,Francoise M. Parrot-Roulaud,Kok Soon Tan,I.M. Higgins,Danielle Garcon,Maria Jos Medrano,Mirande Candito,Alun Evans,Generoso Andria +27 more
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Low Circulating Folate and Vitamin B6 Concentrations Risk Factors for Stroke, Peripheral Vascular Disease, and Coronary Artery Disease
Killian Robinson,Kristopher L. Arheart,Helga Refsum,Lars Brattström,Godfried H.J. Boers,Per Magne Ueland,Paolo Rubba,Roberto Palma-Reis,Raymond Meleady,Leslie Daly,Jacqueline C.M. Witteman,Ian D. Graham +11 more
TL;DR: In this paper, the authors explored the interrelationships between homocysteine, B vitamins, and vascular diseases and evaluated the role of these vitamins as risk factors for atherosclerosis.
Journal ArticleDOI
Homocysteine and Risk of Premature Coronary Heart Disease Evidence for a Common Gene Mutation
Paula M. Gallagher,Raymond Meleady,Denis C. Shields,Kok Soon Tan,Dorothy McMaster,Rima Rozen,Alun Evans,Ian D. Graham,Alexander S. Whitehead +8 more
TL;DR: Plasma total homocysteine levels were significantly associated with disease status, a relationship that matched the strength of the association between disease and homozygous inheritance of the defective enzyme.
Journal ArticleDOI
Genetic analysis of the thermolabile variant of 5, 10-methylenetetrahydrofolate reductase as a risk factor for ischemic stroke.
Dawn L. Harmon,Rachael M. Doyle,Raymond Meleady,Marguerite Doyle,Denis C. Shields,Rosemary Barry,Davis Coakley,Ian D. Graham,Alexander S. Whitehead +8 more
TL;DR: The data indicate that the homozygous C677T MTHFR genotype is at most a moderate risk factor for ischemic stroke.