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Rebecca Rhinehart
Researcher at Fred Hutchinson Cancer Research Center
Publications - 2
Citations - 1927
Rebecca Rhinehart is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Cytotoxic T cell & T cell. The author has an hindex of 2, co-authored 2 publications receiving 1861 citations.
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Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB
Veronika Groh,Rebecca Rhinehart,Heather Secrist,Stefan Bauer,Kenneth H. Grabstein,Thomas A. Spies +5 more
TL;DR: MICA/B are tumor-associated antigens that can be recognized, in an apparently unconditional manner, by a subset of tumor-infiltrating γδ T cells, and raise the possibility that an induced expression of Mica/B, by conditions that may be related to tumor homeostasis and growth, could play a role in immune responses against tumors.
Journal ArticleDOI
Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells.
Veronika Groh,Rebecca Rhinehart,Julie Randolph-Habecker,Max S. Topp,Stanley R. Riddell,Thomas Spies +5 more
TL;DR: Infection by cytomegalovirus resulted in substantial increases in MIC on cultured fibroblast and endothelial cells and was associated with induced MIC expression in interstitial pneumonia, and NKG2D functioned as a costimulatory receptor that can substitute for CD28.